Rare disease ethics: what do patients and doctors really think about personalized trials?

NCT ID NCT07314736

First seen Jun 24, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study interviews patients, families, healthcare providers, and researchers to learn their views on the ethical challenges of small-scale, personalized treatment trials for rare neurological diseases. About 385 participants will share their perspectives through semi-structured interviews. The goal is to develop a best-practice framework for conducting these trials ethically, focusing on informed consent, risk-benefit assessments, and fairness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could create a best-practice framework for conducting ethical personalized treatment trials for children with rare neurological diseases.
What could go wrong
This is an observational interview study, not a treatment trial. It will not directly test any therapy or improve any patient's condition.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Email: •••••@•••••

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