New drug cocktail shows promise for Tough-to-Treat blood cancers

NCT ID NCT04447027

First seen Jan 31, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This early-phase trial tested a combination of four drugs (romidepsin, CC-486, dexamethasone, and lenalidomide) in 26 adults with T-cell cancers that had come back or stopped responding to standard treatments. The main goal was to find a safe dose and check for side effects. Researchers also looked at whether the treatment shrank tumors. This is not a cure, but aims to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.