New hope for rare brain disorder: experimental drug enters final testing phase

NCT ID NCT07224581

Recruiting now Disease control Sponsor: GRIN Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug called radiprodil can help control seizures and improve daily living skills in children with GRIN-related neurodevelopmental disorder, a rare genetic condition. About 100 participants will be randomly assigned to receive either the active drug or a placebo for several months, with the option for all to receive the drug afterward. The main goals are to see if radiprodil reduces seizure frequency and is safe for long-term use.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Child Neurology Consultants of Austin - South Austin
RECRUITING

Austin, Texas, 78757, United States
Children's Hospital Colorado - Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Children's National Hospital
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Cincinnati Children's Hospital Medical Center
NOT_YET_RECRUITING

Cincinnati, Ohio, 45229, United States
Columbia University - Harkness
RECRUITING

New York, New York, 10032, United States
Duke Health-Duke Children's Hospital & Health Center
RECRUITING

Durham, North Carolina, 27705, United States
Iowa Health Care - Pediatric Neurology & Specialty Clinic
RECRUITING

Iowa City, Iowa, 52242, United States
Lucile Packard Children's Hospital
RECRUITING

Palo Alto, California, 94304, United States
Nicklaus Children's Hospital
RECRUITING

Miami, Florida, 33155, United States
Northeast Regional Epilepsy Group (NEREG) - Hackensack
RECRUITING

Hackensack, New Jersey, 07601, United States
Pediatric Neurology and Epilepsy
RECRUITING

Winter Park, Florida, 32789, United States
Seattle Children's Hospital
RECRUITING

Seattle, Washington, 98105, United States
The University of Texas Southwestern Medical Center (UTSW)
NOT_YET_RECRUITING

Dallas, Texas, 75390, United States
UCLA Clinical & Translational Research Center
RECRUITING

Los Angeles, California, 90095, United States
UTHealth Houston
RECRUITING

Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.