New combo aims to boost CAR-T safety in lymphoma patients

NCT ID NCT07478848

First seen Mar 28, 2026 · Last updated Jun 09, 2026 · Updated 15 times

Summary

This early-stage trial tests whether giving radiation therapy and the antibiotic vancomycin before CAR-T cell therapy is safe and doable for people with large B-cell lymphoma. About 14 adults whose lymphoma has not responded or has come back will receive this combination. The goal is to see if this approach reduces side effects like cytokine release syndrome while still helping the CAR-T cells work.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Abramson Cancer Center, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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