New combo therapy targets rare bone cancer with immune-boosting drug

NCT ID NCT07115667

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This study tests whether combining radiation with a bispecific antibody (CM336) can safely treat solitary bone plasmacytoma that has mild bone marrow involvement. About 21 adults with this rare plasma cell disorder will receive the combination therapy. The goal is to control the disease and prevent it from progressing to multiple myeloma, but ongoing monitoring is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences

    RECRUITING

    Tianjin, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.