Promising new rabies vaccine passes phase 3 test

NCT ID NCT03965962

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 3 trial tested a new rabies vaccine (VRVg-2) in 640 healthy adults in France. Participants received the vaccine along with rabies immune globulin, mimicking a real post-exposure scenario. The study found that VRVg-2 produced protective antibody levels as effectively as two existing rabies vaccines. The results suggest VRVg-2 could be a safe and effective option for preventing rabies after exposure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Purified Vero Rabies Vaccine - Serum Free (VRVg-2)

What this could lead to

If successful, this could provide a new, safe, and effective rabies vaccine option for people exposed to the virus.

What could go wrong

This trial was completed in healthy adults in France, so results may not apply to everyone. Rabies is rare in developed countries, and the vaccine's performance in real-world exposure settings may differ.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rabies prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number 2500001

    Rennes, 35000, France

  • Investigational Site Number 2500002

    Gières, 38610, France