New drug combo shows promise for rare bone marrow failure
NCT ID NCT00471848
First seen May 13, 2026 · Last updated May 15, 2026 · Updated 1 time
Summary
This study tested a combination of rabbit antithymocyte globulin (ATG) and ciclosporin in 35 people with acquired aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal was to see if this treatment could improve blood counts and reduce the need for transfusions. Participants received the drugs as their first treatment, and their responses were compared to historical patients who received a horse-derived ATG instead.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Addenbrooke's Hospital
Cambridge, United Kingdom
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Henri Mondor Hospital
Créteil, France
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Hopital St. Louis
Paris, 75475, France
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King Faisal Specialist Hospital & Research Cnetre
Riyadh, Saudi Arabia
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King's College Hospital
London, United Kingdom
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Medical University Hannover
Hanover, Germany
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Nottingham Universitry Hospital Trust
Nottingham, United Kingdom
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Ospedale San Martino
Genova, 16132, Italy
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Royal Bournemouth
Bournemouth, United Kingdom
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St George's Hospital/ St George's University of London
London, Sw17 0RE, United Kingdom
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University Hospital
Basel, 4031, Switzerland
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University Hospital Eppendorf
Hamburg, Germany
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University Hospital Essen
Essen, Germany
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Universitätsklinikum - Institut für klinische Transfusionsmedizin
Ulm, 89081, Germany
Conditions
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