New hope for kids with relapsed AML: targeted drug combo trial opens
NCT ID NCT03793478
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called quizartinib, given with chemotherapy, for children and young adults (ages 1 month to 21 years) whose acute myeloid leukemia (AML) has returned or not responded to treatment. The goal is to see if the combination is safe and can help control the cancer. Participants must have a specific genetic change (FLT3-ITD) in their leukemia cells.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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A.I. duPont Hospital for Children
Wilmington, Delaware, 19803, United States
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British Columbia Children's Hospital
Vancouver, V6H 3V4, Canada
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Centre Léon Bérard
Lyon, 69008, France
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Fondazione IRCCS San Gerardo dei Tintori
Monza, 20900, Italy
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Hospital Infantil Universitario Nino Jesus
Madrid, 28009, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hôpital Armand-Trousseau
Paris, 75012, France
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Hôpital des Enfants
Toulouse, 31300, France
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IRCCS Ospedale Pediatrico Bambino Gesù
Rome, 00165, Italy
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Loma Linda University Cancer Center
Loma Linda, California, 92354, United States
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Ospedale Infantile Regina Margherita
Torino, 10126, Italy
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Prinses Maxima Centrum voor Kinderoncologie
Utrecht, 3584 EA, Netherlands
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Rambam Medical Center
Haifa, 31096, Israel
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Rigshospitalet
Copenhagen, 2100, Denmark
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Sahlgrenska Universitetssjukhuset - Drottning Silvias Barn- och Ungdomssjukhus
Gothenburg, 41685, Sweden
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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Tel Aviv Sourasky Medical Center
Tel Aviv, 64239, Israel
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The Hospital for Sick Children
Toronto, Ontario, M5G1X8, Canada
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The University of Texas Southwestern Medical Center Children's Health
Dallas, Texas, 75390, United States
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UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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Universitair Ziekenhuis Gent
Ghent, Belgium
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University of California, San Francisco
San Francisco, California, 94158, United States
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University of Minnesota/Masonic Cancer Center
Minneapolis, Minnesota, 55455, United States