New hope for kids with relapsed leukemia: experimental drug quizartinib tested in trial

NCT ID NCT03793478

First seen Apr 06, 2026 · Last updated May 16, 2026 · Updated 5 times

Summary

This study tests an experimental drug called quizartinib in children and young adults (ages 1 month to 21 years) with a specific type of leukemia (FLT3-ITD AML) that has returned or not responded to treatment. The drug is given with chemotherapy to see if it can help achieve remission, and then continued alone to keep the cancer under control. The goal is to manage the disease, not cure it, as ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • A.I. duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • British Columbia Children's Hospital

    Vancouver, V6H 3V4, Canada

  • Centre Léon Bérard

    Lyon, 69008, France

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Fondazione IRCCS San Gerardo dei Tintori

    Monza, 20900, Italy

  • Hospital Infantil Universitario Nino Jesus

    Madrid, 28009, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hôpital Armand-Trousseau

    Paris, 75012, France

  • Hôpital des Enfants

    Toulouse, 31300, France

  • IRCCS Ospedale Pediatrico Bambino Gesù

    Rome, 00165, Italy

  • Loma Linda University Cancer Center

    Loma Linda, California, 92354, United States

  • Ospedale Infantile Regina Margherita

    Torino, 10126, Italy

  • Prinses Maxima Centrum voor Kinderoncologie

    Utrecht, 3584 EA, Netherlands

  • Rambam Medical Center

    Haifa, 31096, Israel

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • Sahlgrenska Universitetssjukhuset - Drottning Silvias Barn- och Ungdomssjukhus

    Gothenburg, 41685, Sweden

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, 64239, Israel

  • The Hospital for Sick Children

    Toronto, Ontario, M5G1X8, Canada

  • The University of Texas Southwestern Medical Center Children's Health

    Dallas, Texas, 75390, United States

  • UPMC Children's Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, 15224, United States

  • Universitair Ziekenhuis Gent

    Ghent, Belgium

  • University of California, San Francisco

    San Francisco, California, 94158, United States

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.