New drug targets Hard-to-Treat cancers with KRAS G12V mutation
NCT ID NCT06715124
First seen Mar 04, 2026 · Last updated May 12, 2026 · Updated 8 times
Summary
This early-phase study tests a new drug called QTX3544, alone or with another drug, in people with advanced solid tumors that have a specific KRAS G12V gene change. The main goals are to check safety and find the right dose. About 237 adults with tumors that have not responded to prior therapy will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke Cancer Center
Durham, North Carolina, 27705, United States
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Florida Cancer Specialists & Research Institute
Sarasota, Florida, 34232, United States
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Huntsman Cancer Institute, University of Utah
Salt Lake City, Utah, 84112, United States
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Sarah Cannon Research Institute
Denver, Colorado, 80218, United States
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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South Texas Accelerated Research Therapeutics Mountain Region, LLC
West Valley City, Utah, 84119, United States
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South Texas Accelerated Research Therapeutics, LLC Midwest
Grand Rapids, Michigan, 49546, United States
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South Texas Accelerated Research Therapeutics, LLC San Antonio
San Antonio, Texas, 78229, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Yale Cancer Center
New Haven, Connecticut, 06511, United States
Conditions
Explore the condition pages connected to this study.