New shot could control blood pressure for months

NCT ID NCT06857955

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Dec 26, 2025 · Last updated May 13, 2026 · Updated 19 times

Summary

This study tests an experimental drug called QCZ484, given as a shot under the skin every 6 months, to see if it can safely lower blood pressure in people with mild to moderate hypertension. About 380 adults aged 18 to 75 who are not on blood pressure meds or are on up to two medications will participate. The main goal is to measure changes in average blood pressure over 24 hours after 3 months of treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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AA Medical Research Center
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Flint, Michigan, 48504, United States

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ALL Medical Research LLC
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Cooper City, Florida, 33024, United States

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AMR Las Vegas
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Las Vegas, Nevada, 89119, United States

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AMR Layton
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Layton, Utah, 84041, United States

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Accellacare of Rocky Mount
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Rocky Mount, North Carolina, 27804, United States

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Accellacare of Salisbury
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Salisbury, North Carolina, 28144, United States

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Alliance for Multispecialty Research
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Wichita, Kansas, 67207, United States

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American Research Centers of FL
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Pembroke Pines, Florida, 33027, United States

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Anderson Medical Research
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Ft. Washington, Maryland, 20744, United States

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Ascension Saint Agnes Heart Care
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Baltimore, Maryland, 21229, United States

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Biopharma Informatic
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Katy, Texas, 77479, United States

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Burke Primary Care
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Morganton, North Carolina, 28655, United States

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CR Services Acquisition US
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Columbus, Ohio, 43213, United States

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Capitol Cardiology Associates
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Lanham, Maryland, 20706, United States

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Cardiology Partners Clinical Research Institute
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Wellington, Florida, 33449, United States

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Cedar Crosse Research Ct
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Chicago, Illinois, 60607, United States

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Cen Exel FCR
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Tampa, Florida, 33613, United States

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Cen Exel RCA
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Hollywood, Florida, 33024, United States

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CenExel HRI
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Berlin, New Jersey, 08009, United States

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Centricity Research
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Columbus, Georgia, 31904, United States

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Centricity Research Suffolk Fam Med
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Suffolk, Virginia, 23435, United States

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Clin Rsrch Consult a JCCT Company
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Kansas City, Missouri, 64111, United States

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Clinical Neuroscience Solutions Inc
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Memphis, Tennessee, 38119, United States

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Clinical Research of Brandon LLC
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Brandon, Florida, 33511, United States

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Clinical Trials Research Sacramento
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Sacramento, California, 95821-2134, United States
Clinical Trials of Texas
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San Antonio, Texas, 78229, United States

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Conrad Clinical Research
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Edmond, Oklahoma, 73013, United States

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David M Headley Clinic
WITHDRAWN

Port Gibson, Mississippi, 39150, United States
Dominion Medical Associates
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Richmond, Virginia, 23219, United States

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Downtown L A Research Center Inc
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Los Angeles, California, 90017, United States

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Eagle Clinical Research
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Chicago, Illinois, 60621, United States

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East Coast Institute for Research
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Jacksonville, Florida, 32216, United States

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Elite Clinical Studies
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Phoenix, Arizona, 85018, United States

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Encompass Clinical Research
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Spring Valley, California, 91978-1522, United States

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Entrust Clinical Research
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Miami, Florida, 33176, United States

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Healthcare Research Network II LLC
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Hazelwood, Missouri, 63042, United States

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Inpatient Research Clinical LLC
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Miami Lakes, Florida, 33014, United States
Inpatient Research Clinical LLC
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Miami Lakes, Florida, 33014, United States

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Javara Research
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Fayetteville, Georgia, 30214, United States
Javara Research
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Fayetteville, Georgia, 30214, United States

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Jefferson City Medical Group
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Jefferson City, Missouri, 65109, United States

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Longwood Research
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Huntsville, Alabama, 35801, United States

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Manassas Clinical Research Center
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Manassas, Virginia, 20110, United States

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Monroe Biomedical Research
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Monroe, North Carolina, 28112, United States

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MultiCare Ins Research Innovation
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Puyallup, Washington, 98372, United States

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NICRs Research Center
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Garden Grove, California, 92844, United States

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National Research Institute
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Hialeah, Florida, 33013, United States

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North Hills Medical Research Inc
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Bedford, Texas, 76021, United States

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Novant Health Heart Vas Inst
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Charlotte, North Carolina, 28204, United States

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Novartis Investigative Site
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Suita, Osaka, 5650853, Japan
Novartis Investigative Site
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Chuo Ku, Tokyo, 103-0027, Japan
Novartis Investigative Site
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Chuo Ku, Tokyo, 104-0031, Japan
Novartis Investigative Site
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Chuo-ku, Tokyo, 1030027, Japan
Novartis Investigative Site
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Shinjuku Ku, Tokyo, 160-0008, Japan
Novartis Investigative Site
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Singapore, 119074, Singapore
Novartis Investigative Site
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Singapore, 308433, Singapore
Novartis Investigative Site
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Singapore, 519466, Singapore
Novartis Investigative Site
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Singapore, 529889, Singapore
Oakland Medical Research Center
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Troy, Michigan, 48085, United States

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Renstar Medical Research
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Ocala, Florida, 34471, United States

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SEC Clinical Research LLC
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Andalusia, Alabama, 36420, United States

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Solaris Clinical Research
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Meridian, Idaho, 83646, United States

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Southern Clin Research Clinic
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Zachary, Louisiana, 70791, United States

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Sun Research Institute
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San Antonio, Texas, 78205, United States

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Suncoast Clinical Research
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New Port Richey, Florida, 34452, United States

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Synergy Group Medical LLC
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Houston, Texas, 77061, United States

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Synergy Groups Medical LLC
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Missouri City, Texas, 77459, United States

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Synexus Clinical Research US
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Evansville, Indiana, 47714, United States

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Synexus Clinical Research US Inc
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Tucson, Arizona, 85741, United States

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Synexus Clinical Research US Inc
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Richfield, Minnesota, 55432, United States

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TCV Clinical Studies
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Linwood, Pennsylvania, 19061, United States

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The Center for Clinical Trials
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Saraland, Alabama, 36571, United States

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Trinity Health Michigan Heart
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Ypsilanti, Michigan, 48197, United States

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UAB St Vincents
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Birmingham, Alabama, 35211, United States

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Valiance Clinical Research
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Huntington Park, California, 90255, United States

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Velocity Clin Research Sioux City
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Sioux City, Iowa, 51106, United States

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Velocity Clin at Pioneer Heart Inst
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Lincoln, Nebraska, 68506, United States

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Velocity Clinical Res Baton Rouge
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Baton Rouge, Louisiana, 70809, United States

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Velocity Clinical Research
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Savannah, Georgia, 31406, United States

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Velocity Clinical Research
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Binghamton, New York, 13905, United States

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Velocity Clinical Research
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Union, South Carolina, 29379, United States

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Velocity Clinical Research Austin
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Austin, Texas, 78759, United States

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Velocity Clinical Research Medford
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Medford, Oregon, 97504, United States

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Velocity Clinical Research Spokane
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Spokane, Washington, 99218, United States

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Conditions

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HYPERTENSION