Can a nerve drug get your gut moving again after surgery?
NCT ID NCT05334485
First seen Jan 08, 2026 · Last updated May 16, 2026 · Updated 21 times
Summary
This study tests whether the drug pyridostigmine can safely help the bowel start working again in people who develop a temporary bowel blockage (ileus) after colorectal surgery. About 50 adults who have had elective colon or rectal surgery and then develop ileus will receive either pyridostigmine or a placebo, along with standard care. The main goals are to see how quickly bowel function returns and to monitor any side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic Main Campus
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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