Heart procedure put to the test: sham surgery reveals truth about AF treatment
NCT ID NCT05119231
First seen Nov 19, 2025 · Last updated May 16, 2026 · Updated 22 times
Summary
This study compares a standard heart procedure called pulmonary vein isolation (PVI) to a fake (sham) procedure in 262 people with atrial fibrillation. The goal is to see if the real procedure actually reduces symptoms and improves quality of life more than the placebo effect. Participants will be randomly assigned to receive either PVI or the sham procedure and will be followed for 12 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Department of Cardiology, Silesian Center for Heart Diseases
Zabrze, Poland
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German Heart Center of Charité University Medicine, Standort Charité Mitte
Berlin, State of Berlin, Germany
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German Heart Center of Charité University Medicine, Standort DHZB
Berlin, State of Berlin, Germany
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Heart Center Dresden University Hospital
Dresden, Saxony, 01307, Germany
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Herzzentrum Leipzig
Leipzig, Germany
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Regiomed Klinikum
Coburg, Bavaria, 96450, Germany
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University Hospital Gießen
Giessen, Hesse, Germany
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Universitätsklinikum Leipzig
Leipzig, Germany
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Universitätsklinikum Münster
Münster, North Rhine-Westphalia, 48149, Germany
Conditions
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