New hope for aggressive blood cancer: experimental drug faces off against standard therapy

NCT ID NCT07011056

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 25 times

Summary

This study compares two drugs for people with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments. About 390 adults will receive either purinostat mesylate (given by IV) or selinexor (taken as a pill). The goal is to see which drug works better at shrinking tumors and helping people live longer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West China Hospital Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610200, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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