Ambulance steroid shot may cut heart attack deaths in major trial

NCT ID NCT07478003

First seen Mar 18, 2026 · Last updated May 23, 2026 · Updated 11 times

Summary

This study tests whether a single high-dose steroid (methylprednisolone) given in the ambulance before emergency heart artery opening can reduce deaths in people having a severe heart attack (STEMI). About 5,200 adults with chest pain and signs of a major heart attack will be randomly assigned to receive the steroid or a placebo. The goal is to see if calming inflammation early can limit heart damage and improve survival.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg University Hospital

    NOT_YET_RECRUITING

    Aalborg, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Odense University Hospital

    NOT_YET_RECRUITING

    Odense, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Skejby, Aarhus University Hospital

    NOT_YET_RECRUITING

    Aarhus, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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