New gel could ease painful skin growths

NCT ID NCT07552077

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a gel called PTX-022 (sirolimus) on people aged 6 and older with angiokeratomas, which are small, raised skin spots. The study will check if the gel is safe and helps improve the appearance of these spots. Fifteen participants will apply the gel and be monitored for side effects and changes in their skin.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Sirolimus topical gel (PTX-022)
What this could lead to
If successful, this gel could offer a non-invasive treatment option for angiokeratomas, potentially reducing the need for more aggressive procedures.
What could go wrong
This is a small, early-phase trial with only 15 participants, so results may not apply widely. The gel may cause skin irritation or not improve the condition significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleaver Medical Group

    RECRUITING

    Dawsonville, Georgia, 30534, United States

  • Epiphany Dermatology

    RECRUITING

    Southlake, Texas, 76092, United States

  • Unified Health

    NOT_YET_RECRUITING

    Sherman Oaks, California, 91403, United States

  • Vividia Dermatology

    NOT_YET_RECRUITING

    Las Vegas, Nevada, 89148, United States