New drug trial targets tough digestive cancers

NCT ID NCT05482893

Summary

This early-stage study is testing a new drug called PT886 (spevatamig) in people with advanced stomach, pancreatic, or bile duct cancers that have spread or cannot be removed by surgery. The main goals are to find a safe dose, check for side effects, and see if the drug shows early signs of helping when given alone or with standard chemotherapy. The study is enrolling adults whose cancer has a specific marker called CLDN18.2.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center)

    RECRUITING

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute (DFCI)

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02215, United States

  • Duke Cancer Center

    RECRUITING

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center, GI Medical Oncology Dept

    RECRUITING

    Houston, Texas, 77030, United States

  • NEXT Oncology

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Norton Cancer Institute

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • Sarah Cannon Research Institute (SCRI)

    RECRUITING

    Denver, Colorado, 80218, United States

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Pittsburgh Medical Center (UPMC)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Wisconsin Carbone Cancer Center - University Hospital

    RECRUITING

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.