Magic mushroom therapy takes on meth addiction in veterans
NCT ID NCT04982796
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether psilocybin, the active ingredient in magic mushrooms, combined with psychotherapy can help veterans with moderate to severe methamphetamine use disorder. Thirty participants will receive either psilocybin-enhanced therapy or standard treatment. The study focuses on whether the approach is safe, acceptable, and feasible, not yet on proving it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If this works, it could point toward a new treatment option for methamphetamine use disorder, potentially helping people reduce or stop use.
What could go wrong
This is a very early, small proof-of-concept study with only 30 veterans. It primarily measures safety and feasibility, not effectiveness. Psilocybin may cause adverse events or not show benefit over usual care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Portland VA Health Care System
Vancouver, Washington, 98661, United States