New pill targets genetic weakness in advanced cancers

NCT ID NCT06560645

Summary

This early-stage study tested a new oral drug called PRT7732 in people with advanced or metastatic solid tumors that have a specific genetic change (SMARCA4 mutation). The main goals were to find a safe dose, see how the body processes the drug, and look for early signs that it might help control the cancer. The study was for patients whose cancer had progressed on standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Border Medical Oncology Research Unit

    Albury, New South Wales, 2640, Australia

  • Brigitte Harris Cancer Pavilion

    Detroit, Michigan, 48202, United States

  • Cancer Institute Hospital of JFCR

    Koto-ku, Tokyo, 135-8550, Japan

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Kindai University Hospital

    Sayama, Osaka, 589-8511, Japan

  • Linear Clinical Research Ltd

    Nedlands, Western Australia, 6009, Australia

  • Memorial Sloan Kettering Cancer Center - Main Campus

    New York, New York, 10065, United States

  • Monash Health

    Clayton, Victoria, 3168, Australia

  • National Cancer Center

    Goyang-si, Gyeonggi-do, 10408, South Korea

  • National Cancer Center Hospital

    Chuo Ku, Tokyo, 104-0045, Japan

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Scientia Clinical Research Ltd

    Randwick, New South Wales, 2031, Australia

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • Southern Highlands Cancer Centre

    Bowral, New South Wales, 2576, Australia

  • Start Madrid-FJD, Hospital Universitario Fundacion Jimenez Diaz-Servicio de Oncologia

    Madrid, 28040, Spain

  • Technische Universitat Dresden, Medizinlsche Fakultat Carl Gustav Carus Nationales Centrum fur Tumorerkrankungen Dresden, Early Clinical Trial Unit (NCT/UCC ECTU)

    Dresden, Saxony, 01307, Germany

  • The Univerity of Osaka Hospital

    Suita, Osaka, 565-0871, Japan

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94158, United States

  • UNC Hospitals, The University of North Carolina Chapel Hill

    Chapel Hill, North Carolina, 27514, United States

  • University Clinic Cologne, Clinic for Internal Medicine

    Cologne, North Rhine-Westfalia, 50937, Germany

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Virginia Comprehensive Cancer Center

    Charlottesville, Virginia, 22903, United States

Conditions

Explore the condition pages connected to this study.