New voice valve may cut frequent replacements for throat cancer survivors
NCT ID NCT07369050
First seen Jan 27, 2026 · Last updated Jun 15, 2026 · Updated 25 times
Summary
This study looks at whether using the Provox ActiValve voice prosthesis as a first-choice device can lower the number of replacements needed each year in people who have had their voice box removed (total laryngectomy) and a tracheoesophageal puncture (TEP). About 48 adults who are at least 6 months past cancer treatment and currently use or are ready for an indwelling voice prosthesis will be randomly assigned to get either the ActiValve or a standard device. The main goal is to see if the ActiValve leads to fewer device changes and fewer side effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77090, United States
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