Can a side of protein unlock the nutrients in your salad?
NCT ID NCT07795372
First seen Aug 31, 2026 · Last updated Sep 03, 2026 · Updated 3 times
Summary
Researchers at the National University of Singapore are testing whether eating a salad with chicken, tuna, egg, or soybean changes how much carotenoid your body absorbs. Carotenoids are pigments in vegetables that act as antioxidants. The study enrolls healthy Singaporean adults aged 21 to 45. Participants eat a salad alone or with one of the four proteins, and researchers measure carotenoid and triglyceride levels in their blood afterward.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Salad with a protein source (chicken, tuna, egg, or soybean) compared with salad alone
- What this could lead to
- If it works, this could point toward simple meal combinations that help people absorb more carotenoids from vegetables, supporting better nutrition without supplements.
- What could go wrong
- This is a small, early study with 19 healthy adults, so results may not apply to everyone. The effect of protein on carotenoid absorption could also be small or vary by protein type.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 19 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. English-literate and able to give informed consent 2. Singaporean Adults aged 21 to 45 (inclusive) 3. Body mass index of 18.5 to 23.0 kg/m2 (inclusive) 4. At least 50 kg 5. Healthy (based on screening results) Exclusion Criteria: 1. Currently participating in another clinical study that involves altering regular diet and/or involves consuming a dietary supplement or investigated food product as an intervention 2. High blood pressure (≥ 140/90 mmHg) 3. Underlying health conditions that may affect metabolic functions 4. Consuming carotenoid supplements regularly (i.e., more than three times a week) for the past 3 months, and not willing to discontinue consumption 3 months before and during the study duration 5. Weight change \> 3 kg in the past 3 months 6. Exercising vigorously over the past 3 months (i.e., engaging in high-intensity exercises for more than 3 hours a week, where high-intensity exercises leave one out of breath and unable to talk or sing during the workout) 7. Current smokers or have quit smoking for less than 5 years 8. Drinking \> 2 alcoholic drinks per day (i.e., one drink is defined as either 150 ml of wine, 340 ml of beer/cider or 45 ml of distilled spirit) 9. If drinking ≤ 2 alcoholic drinks per day, not willing to stop consumption of alcoholic beverages two days before and on the day of the test visits 10. Not willing to stop consumption of caffeinated beverages 10 to 12 hours before and on the day of the test visits 11. Currently on a specialised diet (e.g., vegetarian, vegan, weight loss diet) 12. Had serious food allergies in the past, or having intolerance, sensitivities or allergies to any of the following: soy/soy-derived products, eggs, fish and crustaceans, starch/starch-derived products (e.g., rice, corn, wheat, potato), gluten 13. Disease or impairment of the liver 14. Currently diagnosed with diabetes, gastrointestinal issues (e.g., lactose intolerance, irritable bowel syndrome), gout and/or G6PD deficiency 15. Taking antibiotics 2 weeks prior to study participation 16. Taking anti-hypertensive or cholesterol-lowering drugs for less than 3 years unless medically declared by an official doctor to be in stable condition 17. Poor peripheral venous access based on past experiences with blood drawing 18. Individuals with pacemaker or related electrical medical devices 19. Pregnant, lactating, or planning pregnancy in the next 6 months 20. Have donated blood (whole blood or apheresis) or participated in any other clinical study or trial requiring blood draws within the last 3 months 21. Clinical anemia (hemoglobin \<12.0 g/dL in women and \<13.0 g/dL in men)
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07, Singapore, 117542
Singapore, 117542, Singapore