New Two-Pronged attack tested for tough prostate cancer

NCT ID NCT05682443

Summary

This study is testing whether adding a new immunotherapy drug called ONC-392 to an existing prostate cancer radiation treatment (Pluvicto) is safe and more effective. It is for men whose advanced prostate cancer has worsened despite prior hormone-blocking drugs and chemotherapy. The main goal is to see if the combination can better control the cancer's growth and extend the time patients live without their disease getting worse.

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Contacts and locations

Locations

  • Chesapeake Urology Research Associates

    Towson, Maryland, 21204, United States

  • Columbia University Irving Cancer Center

    New York, New York, 10032, United States

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • Emory University Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Lahey Hospital & Medical Center

    Burlington, Massachusetts, 01805, United States

  • Moffitt Cancer Cancer

    Tampa, Florida, 33612, United States

  • NYU Langone Health, Laura & Isaac Perlmutter Cancer Center

    New York, New York, 10016, United States

  • New Mexico Oncology Hematology Consultants

    Albuquerque, New Mexico, 87109, United States

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97210, United States

  • Oncology and Hematology Associates Of Southwest Virginia USOR

    Norton, Virginia, 24273, United States

  • Rocky Mountain Cancer Centers USOR

    Aurora, Colorado, 80012, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14203, United States

  • Rutgers Cancer Institute

    New Brunswick, New Jersey, 08901, United States

  • The Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21202, United States

  • UC Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • UNC North Carolina Comprehensive Cancer Care Center

    Chapel Hill, North Carolina, 27514, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • UW Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • Virginia Cancer Specialists USOR

    Fairfax, Virginia, 22031, United States

  • Virginia Oncology Associates USOR

    Norfolk, Virginia, 23502, United States

  • XCancer/GU Research Network

    Omaha, Nebraska, 68130, United States

Conditions

Explore the condition pages connected to this study.