New hope for tough prostate cancer: experimental drug trial opens

NCT ID NCT06353386

Recruiting now Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug called MK-5684, both alone and in combination with other treatments, for men with advanced prostate cancer that has spread and no longer responds to standard hormone therapy. The main goals are to find a safe dose and see if the drug can help control the cancer. About 220 participants will join this early-phase trial to help researchers understand if this approach is effective.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aalborg Universitetshospital, Syd ( Site 0503)
RECRUITING

Aalborg, North Denmark, 9000, Denmark

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Addenbrooke's Hospital ( Site 1902)
RECRUITING

Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom

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Ankara Bilkent Şehir Hastanesi ( Site 1801)
RECRUITING

Ankara, 06800, Turkey (Türkiye)

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Asan Medical Center-Oncology ( Site 1500)
RECRUITING

Songpagu, Seoul, 05505, South Korea

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Auckland City Hospital ( Site 1333)
RECRUITING

Auckland, 1023, New Zealand

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Azienda Ospedaliera Universitaria Integrata Verona - Ospedal-Centro Ricerche Cliniche di Verona ( Site 1100)
RECRUITING

Verona, 37134, Italy

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Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1802)
RECRUITING

Adana, 01250, Turkey (Türkiye)

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Bradfordhill ( Site 0300)
RECRUITING

Santiago, Region M. de Santiago, 8420383, Chile

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CIDO SpA-Oncology ( Site 0302)
RECRUITING

Temuco, Región del Biobío, 4810218, Chile

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Centre Hospitalier de l'Université de Montréal ( Site 0200)
RECRUITING

Montreal, Quebec, H2X 3E4, Canada

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Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0207)
RECRUITING

Québec, Quebec, G1J 1Z4, Canada

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Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1402)
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland

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Chang Gung Medical Foundation-Linkou Branch-Medical Oncology ( Site 1702)
RECRUITING

Taoyuan District, 333, Taiwan

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Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 1704)
RECRUITING

Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan

Contact Phone: •••-•••-••••
Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0800)
ACTIVE_NOT_RECRUITING

Berlin, 10117, Germany
China Medical University Hospital ( Site 1703)
RECRUITING

Taichung, 404332, Taiwan

Contact Phone: •••-•••-••••
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 0402)
RECRUITING

Bogotá, Bogota D.C., 111321, Colombia

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Clinica Universidad Catolica del Maule-Oncology ( Site 0304)
RECRUITING

Talca, Maule Region, 3465584, Chile

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Cork University Hospital ( Site 0902)
RECRUITING

Cork, T12 DC4A, Ireland

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Docrates Syöpäsairaala ( Site 0602)
RECRUITING

Helsinki, Uusimaa, 00180, Finland

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FALP ( Site 0301)
RECRUITING

Santiago, Region M. de Santiago, 7500921, Chile

Contact Phone: •••-•••-••••
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0406)
RECRUITING

Bogotá, Bogota D.C., 110131, Colombia

Contact Phone: •••-•••-••••
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1103)
RECRUITING

Milan, Lombardy, 20133, Italy

Contact Phone: •••-•••-••••
Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1102)
COMPLETED

Rome, Lazio, 00168, Italy
Fundación Valle del Lili-Oncology CIC ( Site 0403)
RECRUITING

Cali, Valle del Cauca Department, 760032, Colombia

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Gallipoli Medical Research Ltd-GMRF CTU ( Site 0107)
RECRUITING

Greenslopes, Queensland, 4120, Australia

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Gustave Roussy ( Site 0701)
RECRUITING

Villejuif, Île-de-France Region, 94805, France

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Hacettepe Universite Hastaneleri-oncology hospital ( Site 1800)
RECRUITING

Ankara, 06230, Turkey (Türkiye)

Contact Phone: •••-•••-••••
Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 0604)
RECRUITING

Helsinki, Uusimaa, 00029, Finland

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Herlev and Gentofte Hospital ( Site 0501)
RECRUITING

Copenhagen, Capital Region, 2730, Denmark

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Hospital Clinico San Carlos-Oncology Department ( Site 1604)
RECRUITING

Madrid, 28040, Spain

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Hospital General Universitario Gregorio Marañón ( Site 1601)
RECRUITING

Madrid, 28007, Spain

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Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1602)
RECRUITING

Barcelona, 08035, Spain

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Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 1600)
RECRUITING

Madrid, Madrid, Comunidad de, 28034, Spain

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Hôpital Européen Georges Pompidou-Service d'Oncologie Médicale ( Site 0702)
RECRUITING

Paris, 75015, France

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IMAT S.A.S ( Site 0404)
RECRUITING

Montería, Departamento de Córdoba, 230002, Colombia

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Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest ( Site 0703)
RECRUITING

Bordeaux, Aquitaine, 33076, France

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Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 1603)
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 08908, Spain

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Institut de cancérologie Strasbourg Europe (ICANS) ( Site 0700)
RECRUITING

Strasbourg, Alsace, 67200, France

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Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1804)
RECRUITING

Istanbul, 34668, Turkey (Türkiye)

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Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1101)
RECRUITING

Rozzano, Milano, 20089, Italy

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Jewish General Hospital ( Site 0206)
RECRUITING

Montreal, Quebec, H3T 1E2, Canada

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Kyushu University Hospital ( Site 1204)
RECRUITING

Fukuoka, 812-8582, Japan

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MEDICAL COLLEGE OF WISCONSIN-Cancer Center Clinical Trials Office ( Site 0020)
RECRUITING

Milwaukee, Wisconsin, 53226, United States

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Macquarie University-MQ Health Clinical Trials Unit ( Site 0108)
RECRUITING

Macquarie University, New South Wales, 2109, Australia

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Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Oddzial Badan Wczesnych Faz ( Site 1400)
RECRUITING

Warsaw, Masovian Voivodeship, 02-781, Poland

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Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0110)
RECRUITING

Melbourne, Victoria, 3000, Australia

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Pontificia Universidad Catolica de Chile ( Site 0303)
RECRUITING

Santiago, Region M. de Santiago, 832000, Chile

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Queen Elizabeth Hospital Birmingham ( Site 1903)
RECRUITING

Birmingham, B15 2TH, United Kingdom

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Rabin Medical Center ( Site 1001)
RECRUITING

Petah Tikva, 4941492, Israel

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Rambam Health Care Campus-Oncology Division ( Site 1002)
RECRUITING

Haifa, 3109601, Israel

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Royal Preston Hospital-Lancashire Clinical Research Facility ( Site 1900)
RECRUITING

Preston, Lancashire, PR2 9HT, United Kingdom

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Rutgers Cancer Institute of New Jersey ( Site 0033)
RECRUITING

New Brunswick, New Jersey, 08903-2681, United States

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Samsung Medical Center-Division of Hematology/Oncology ( Site 1501)
RECRUITING

Seoul, 06351, South Korea

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Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1502)
RECRUITING

Seoul, 03722, South Korea

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Sheba Medical Center ( Site 1000)
RECRUITING

Ramat Gan, 5265601, Israel

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Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0400)
RECRUITING

Valledupar, Cesar Department, 200001, Colombia

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St. Vincent's University Hospital ( Site 0901)
RECRUITING

Dublin, Dublin, D04 T6F4, Ireland

Contact Phone: •••-•••-••••
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1803)
RECRUITING

Istanbul, 34722, Turkey (Türkiye)

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Taipei Veterans General Hospital ( Site 1701)
RECRUITING

Taipei, 112, Taiwan

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Tallaght University Hospital ( Site 0900)
RECRUITING

Dublin, D24 NR0A, Ireland

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The Beatson West of Scotland Cancer Centre ( Site 1904)
RECRUITING

Glasgow, Glasgow City, G12 0YN, United Kingdom

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The Jikei University Hospital ( Site 1202)
COMPLETED

Mitato, Tokyo, 105-8471, Japan
Toho University Sakura Medical Center ( Site 1201)
RECRUITING

Sakura, Chiba, 285-8741, Japan

Contact Phone: •••-•••-••••
UCLA Hematology/Oncology - Santa Monica ( Site 0044)
RECRUITING

Los Angeles, California, 90404, United States

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UCSD Moores Cancer Center ( Site 0039)
RECRUITING

La Jolla, California, 92037, United States

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Universitaetsklinikum Hamburg-Eppendorf-Onkologisches Zentrum ( Site 0804)
RECRUITING

Hamburg, 20246, Germany

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Universitaetsklinikum Heidelberg ( Site 0805)
RECRUITING

Heidelberg, Baden-Wurttemberg, 69120, Germany

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Universitaetsklinikum Tuebingen-Urologie ( Site 0801)
RECRUITING

Tübingen, Baden-Wurttemberg, 72076, Germany

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University College London Hospital ( Site 1905)
RECRUITING

London, London, City of, NW1 2PG, United Kingdom

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University Hospitals Cleveland Medical Center ( Site 0043)
RECRUITING

Cleveland, Ohio, 44106, United States

Contact Phone: •••-•••-••••
University of Maryland-Greenebaum Comprehensive Cancer Center ( Site 0049)
ACTIVE_NOT_RECRUITING

Baltimore, Maryland, 21201, United States
University of Miami Hospital and Clinics, Sylvester Cancer Center-Cancer Research Services ( Site 0051)
RECRUITING

Miami, Florida, 33136, United States

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Uniwersyteckie Centrum Kliniczne ( Site 1405)
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-952, Poland

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Vaasan Keskussairaala ( Site 0603)
RECRUITING

Vaasa, Pohjanmaa, 65130, Finland

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Yokohama City University Medical Center ( Site 1203)
RECRUITING

Yokohama, Kanagawa, 232-0024, Japan

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klinikum rechts der isar der technischen universität münchen-Urologische Klinik und Poliklinik ( Site 0802)
RECRUITING

Munich, Bavaria, 81675, Germany

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

PROSTATIC NEOPLASMS, CASTRATION-RESISTANT