New drug cocktails tested in fight against spreading prostate cancer

NCT ID NCT03431350

Summary

This study is testing several combinations of the drug niraparib with other cancer treatments for men with metastatic castration-resistant prostate cancer (mCRPC), a serious, advanced form of the disease. The main goals are to find safe and effective doses and to see how well these combinations can shrink tumors or control the cancer. The trial involves about 136 participants and is currently active but not recruiting new patients.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, 20162, Italy

  • Asaf Harofe Medical Center

    Beer Yaakov, 60930, Israel

  • Az Groeninge

    Kortrijk, 8500, Belgium

  • Azienda Ospedaliera ''Vito Fazzi''

    Lecce, 73100, Italy

  • Azienda Ospedaliera Universitaria Careggi di Firenze

    Florence, 50134, Italy

  • British Columbia Cancer Agency

    Vancouver, British Columbia, V5Z4E6, Canada

  • Carolina Urologic Research Center

    Myrtle Beach, South Carolina, 29572, United States

  • Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman

    Liège, B-4000, Belgium

  • Centre de Recherche du CHUM

    Montreal, Quebec, H2X 0A9, Canada

  • Chesapeake Urology Research Associates

    Towson, Maryland, 21204, United States

  • First Urology, PSC

    Jeffersonville, Indiana, 47130, United States

  • Hosp Univ Fund Jimenez Diaz

    Madrid, 28040, Spain

  • Hosp Univ Hm Sanchinarro

    Madrid, 28050, Spain

  • Hosp Virgen de La Victoria

    Málaga, 29010, Spain

  • Hosp. Univ. de La Princesa

    Madrid, 28006, Spain

  • Hosp. de La Santa Creu I Sant Pau

    Barcelona, 08025, Spain

  • Hospital Vall D'Hebron

    Barcelona, 8035, Spain

  • Houston Metro Urology

    Houston, Texas, 77027, United States

  • IRCCS-Fondazione Pascale

    Naples, 80131, Italy

  • MUSC-Hollings Cancer Center

    Charleston, South Carolina, 29425, United States

  • Mayo Clinic - Division Of Hematology/oncology

    Jacksonville, Florida, 32224, United States

  • Memorial Sloan Kettering Cancer Center

    Harrison, New York, 10604, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Michigan Institute of Urology

    Troy, Michigan, 48084, United States

  • New York Oncology Hematology

    Albany, New York, 12208, United States

  • OLV Ziekenhuis Aalst

    Aalst, 9300, Belgium

  • Princess Margaret Cancer Centre University Health Network

    Toronto, Ontario, M5G2M9, Canada

  • Rabin Medical Center

    Petah Tikva, 49100, Israel

  • Rambam Medical Center

    Haifa, 31096, Israel

  • Royal Cornwall Hospitals NHS Trust - Royal Cornwall Hospital

    Truro, TR1 3LJ, United Kingdom

  • Royal United Hospital

    Bath, BA1 3NG, United Kingdom

  • Sheba Medical Center Tel Hashomer

    Ramat Gan, 52621, Israel

  • Soroka Hospital

    Beersheba, 85101, Israel

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • Southern Alberta Institute of Urology / Prostate Cancer Centre

    Calgary, Alberta, T2V 1P9, Canada

  • The Royal Marsden NHS Trust Sutton

    Sutton, SM2 5PT, United Kingdom

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • The Urology Center of Colorado

    Denver, Colorado, 80211, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • ULB Hôpital Erasme

    Brussels, 1070, Belgium

  • UOC Oncologia Ospedale Provinciale di Macerata

    Macerata, 62100, Italy

  • Universitair Ziekenhuis Gent

    Ghent, 9000, Belgium

  • University College London Hospitals

    London, WC1E 6BT, United Kingdom

  • University of Pittsburgh Medical Center (UPMC)

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 5379200, United States

  • Urological Associates of Southern Arizona, P.C.

    Tucson, Arizona, 85741, United States

  • Urology Associates

    Nashville, Tennessee, 37209, United States

  • Urology of Virginia, PLCC

    Virginia Beach, Virginia, 23462, United States

  • Utah Cancer Specialists

    Salt Lake City, Utah, 84106, United States

  • ZNA Middelheim

    Antwerp, 2020, Belgium

Conditions

Explore the condition pages connected to this study.