New combo therapy tested to stall prostate Cancer's return

NCT ID NCT01251861

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is for men whose prostate cancer is starting to come back, shown by a rising PSA level, after their initial surgery or radiation. It compares two treatment plans: one uses a standard hormone-blocking drug (bicalutamide) alone, and the other combines that drug with an experimental one (MK-2206) that aims to block cancer cell growth. The main goal is to see which approach is better at lowering PSA to undetectable levels and controlling the cancer longer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
AdventHealth Littleton

Littleton, Colorado, 80122, United States
AdventHealth Parker

Parker, Colorado, 80138, United States
AdventHealth Porter

Denver, Colorado, 80210, United States
Allegiance Health

Jackson, Michigan, 49201, United States
Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494, United States
Atlanta VA Medical Center

Decatur, Georgia, 30033, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Bay Area Medical Center

Marinette, Wisconsin, 54143, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Beacon Kalamazoo

Kalamazoo, Michigan, 49048, United States
Beebe Medical Center

Lewes, Delaware, 19958, United States
Bixby Medical Center

Adrian, Michigan, 49221, United States
Boulder Community Foothills Hospital

Boulder, Colorado, 80303, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
Butler Memorial Hospital

Butler, Pennsylvania, 16001, United States
Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States
Carle BroMenn Medical Center

Normal, Illinois, 61761, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Cancer Institute Normal

Normal, Illinois, 61761, United States
Christiana Care - Union Hospital

Elkton, Maryland, 21921, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Community Howard Regional Health

Kokomo, Indiana, 46904, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital

Saint Joseph, Michigan, 49085, United States
Cork University Hospital

Cork, Ireland
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Essentia Health Cancer Center

Duluth, Minnesota, 55805, United States
Essentia Health Saint Joseph's Medical Center

Brainerd, Minnesota, 56401, United States
Essentia Health Saint Mary's Medical Center

Duluth, Minnesota, 55805, United States
Eureka Hospital

Eureka, Illinois, 61530, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Fisher-Titus Medical Center

Norwalk, Ohio, 44857, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Franciscan Saint Anthony Health-Michigan City

Michigan City, Indiana, 46360, United States
Fredericksburg Oncology Inc

Fredericksburg, Virginia, 22401, United States
Fulton County Health Center

Wauseon, Ohio, 43567, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Center-Cancer Center Hazleton

Hazleton, Pennsylvania, 18201, United States
Geisinger Medical Group

State College, Pennsylvania, 16801, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Genesys Regional Medical Center-West Flint Campus

Flint, Michigan, 48532, United States
Graham Hospital Association

Canton, Illinois, 61520, United States
HSHS Saint Nicholas Hospital

Sheboygan, Wisconsin, 53081, United States
Heartland Cancer Research NCORP

Decatur, Illinois, 62526, United States
Hematology Oncology Associates

Albuquerque, New Mexico, 87106, United States
Hematology Oncology Center Incorporated

Elyria, Ohio, 44035, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
Henry Ford Health Warren Hospital

Warren, Michigan, 48093, United States
Hickman Cancer Center

Adrian, Michigan, 49221, United States
Hinsdale Hematology Oncology Associates Incorporated

Hinsdale, Illinois, 60521, United States
Holy Family Memorial Hospital

Manitowoc, Wisconsin, 54221, United States
Horizon Oncology Research LLC

Lafayette, Indiana, 47905, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
Hutchinson Area Health Care

Hutchinson, Minnesota, 55350, United States
IU Health Central Indiana Cancer Centers-East

Indianapolis, Indiana, 46219, United States
IU Health La Porte Hospital

La Porte, Indiana, 46350, United States
IU Health Methodist Hospital

Indianapolis, Indiana, 46202, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois Valley Hospital

Peru, Illinois, 61354, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Iowa-Wide Oncology Research Coalition NCORP

Des Moines, Iowa, 50309, United States
John H Stroger Jr Hospital of Cook County

Chicago, Illinois, 60612, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Lake Huron Medical Center

Port Huron, Michigan, 48060, United States
Lake Region Healthcare Corporation-Cancer Care

Fergus Falls, Minnesota, 56537, United States
Lakeview Hospital

Stillwater, Minnesota, 55082, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Lima Memorial Hospital

Lima, Ohio, 45804, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
Mason District Hospital

Havana, Illinois, 62644, United States
Mater Misericordiae University Hospital

Dublin, Co Dublin, 7, Ireland
Mater Private Hospital

Dublin, Co Dublin, 7, Ireland
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
Mcdonough District Hospital

Macomb, Illinois, 61455, United States
Memorial Hospital

Carthage, Illinois, 62321, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Memorial Medical Center-Las Cruces

Las Cruces, New Mexico, 88011, United States
Mercy Cancer Center-Elyria

Elyria, Ohio, 44035, United States
Mercy Health - Saint Anne Hospital

Toledo, Ohio, 43623, United States
Mercy Health - Saint Vincent Hospital

Toledo, Ohio, 43608, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital of Tiffin

Tiffin, Ohio, 44883, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Mercy Medical Center-Sioux City

Sioux City, Iowa, 51102, United States
Mercy Memorial Hospital

Monroe, Michigan, 48162, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Michigan Cancer Research Consortium NCORP

Ann Arbor, Michigan, 48106, United States
Miller-Dwan Hospital

Duluth, Minnesota, 55805, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Mount Sinai Union Square

New York, New York, 10003, United States
MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601, United States
Nevada Cancer Research Foundation NCORP

Las Vegas, Nevada, 89120, United States
New Ulm Medical Center

New Ulm, Minnesota, 56073, United States
North Coast Cancer Care

Sandusky, Ohio, 44870, United States
North Coast Cancer Care-Clyde

Clyde, Ohio, 43410, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
North Suburban Medical Center

Thornton, Colorado, 80229, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
Northern Indiana Cancer Research Consortium

South Bend, Indiana, 46628, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Pekin

Pekin, Illinois, 61554, United States
OSF Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States
Ottawa Regional Hospital and Healthcare Center

Ottawa, Illinois, 61350, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Perry Memorial Hospital

Princeton, Illinois, 61356, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066, United States
ProHealth Waukesha Memorial Hospital

Waukesha, Wisconsin, 53188, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

Toledo, Ohio, 43606, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Richard L. Roudebush Veterans Affairs Medical Center

Indianapolis, Indiana, 46202, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Rose Medical Center

Denver, Colorado, 80220, United States
Rush-Copley Medical Center

Aurora, Illinois, 60504, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
Saint Charles Hospital

Oregon, Ohio, 43616, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Hospital - Cancer Centers of Colorado

Denver, Colorado, 80218, United States
Saint Joseph Regional Medical Center-Mishawaka

Mishawaka, Indiana, 46545, United States
Saint Luke's Hospital

Maumee, Ohio, 43537, United States
Saint Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Mary Medical and Regional Cancer Center

Langhorne, Pennsylvania, 19047, United States
Saint Mary's Hospital and Regional Medical Center

Grand Junction, Colorado, 81501, United States
Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301, United States
Saint Vincent's University Hospital

Dublin, Co Dublin, 4, Ireland
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Sidney and Lois Eskenazi Hospital

Indianapolis, Indiana, 46202, United States
Siouxland Regional Cancer Center

Sioux City, Iowa, 51101, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
South Bend Clinic

South Bend, Indiana, 46617, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
Swedish American Hospital

Rockford, Illinois, 61104, United States
Swedish Medical Center

Englewood, Colorado, 80113, United States
Tallaght University Hospital

Dublin, Co Dublin, 24, Ireland
The Medical Center of Aurora

Aurora, Colorado, 80012, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Toledo Clinic Cancer Centers-Bowling Green

Bowling Green, Ohio, 43402, United States
Toledo Clinic Cancer Centers-Maumee

Maumee, Ohio, 43537, United States
Toledo Clinic Cancer Centers-Monroe

Monroe, Michigan, 48162, United States
Toledo Clinic Cancer Centers-Oregon

Oregon, Ohio, 43616, United States
Toledo Clinic Cancer Centers-Toledo

Toledo, Ohio, 43623, United States
Toledo Community Hospital Oncology Program CCOP

Toledo, Ohio, 43617, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341, United States
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
Trinity Medical Center

Moline, Illinois, 61265, United States
Trinity's Tony Teramana Cancer Center

Steubenville, Ohio, 43952, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325, United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University College Hospital Galway

Galway, Co Galway, Ireland
University of Maryland Shore Medical Center at Easton

Easton, Maryland, 21601, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of Toledo

Toledo, Ohio, 43614, United States
VA Palo Alto Health Care System

Palo Alto, California, 94304, United States
Veterans Adminstration New Jersey Health Care System

East Orange, New Jersey, 07018-1095, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Western States Cancer Research NCORP

Denver, Colorado, 80222, United States

Conditions

Explore the condition pages connected to this study.

RECURRENT PROSTATE CARCINOMA STAGE I PROSTATE CANCER AJCC V7 STAGE IIA PROSTATE CANCER AJCC V7 STAGE IIB PROSTATE CANCER AJCC V7 STAGE III PROSTATE CANCER AJCC V7