New trick to tame prostate radiation: shrink the gland first!

NCT ID NCT07251829

Not yet recruiting Symptom relief Sponsor: Srinivas Raman Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a procedure called prostate artery embolization (PAE) can reduce urinary side effects from radiotherapy in men with prostate cancer. Participants have large prostates or existing urinary symptoms. They will receive PAE before starting radiation, and researchers will track changes in urinary function and side effects over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prostatic Artery Embolization (a procedure to shrink the prostate by blocking its blood supply)
What this could lead to: If it works, this could offer a way to reduce urinary problems from radiotherapy, making treatment easier to tolerate for men with larger prostates.
What could go wrong: This is a small, early-phase trial with only 35 participants, so results may not apply to everyone. The procedure itself carries risks like pain or bleeding, and it's not yet clear if it will meaningfully reduce side effects.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE ADENOCARCINOMA

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