Nasal spray vs IV: which sedative better prevents Kids' Post-Dental agitation?
NCT ID NCT06466915
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial compares two drugs—propofol given intravenously and dexmedetomidine given as a nasal spray—to see which better prevents agitation and delirium in children waking up from dental surgery under general anesthesia. About 162 children aged 1-2 on the ASA scale will take part. The goal is to find a safer, more effective way to calm kids and avoid complications like bleeding or delayed discharge.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexmedetomidine (nasal) and propofol (intravenous)
- What this could lead to
- If one drug proves better at calming children after dental surgery, it could reduce complications like bleeding, IV dislodgement, and hospital delays.
- What could go wrong
- This is a single-center, moderate-sized trial. Results may not apply to all children or surgeries, and both drugs carry risks like breathing problems or unstable blood pressure.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ahmed Uslu
Ankara, Çankaya, 06490, Turkey (Türkiye)