New hope for kids with CF: triple therapy shows promise in young patients
NCT ID NCT04613128
First seen Nov 03, 2025 · Last updated May 14, 2026 · Updated 32 times
Summary
This study looked at how well a triple combination therapy (elexacaftor, tezacaftor, and ivacaftor, or ETI) works in children aged 6 to 11 with cystic fibrosis (CF) who have a specific genetic mutation. Researchers measured changes in sweat chloride, lung function, and growth over 24 months. The goal was to understand the therapy's real-world benefits and collect data for future research.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CYSTIC FIBROSIS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
-
Baylor College of Medicine
Houston, Texas, 77030, United States
-
Boston Children's Hospital, Brigham & Women's Hospital
Boston, Massachusetts, 02115, United States
-
Children's Hospital Colorado
Aurora, Colorado, 80045, United States
-
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
-
Children's Mercy Kansas City
Kansas City, Missouri, 64108, United States
-
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
-
John Hopkins University
Baltimore, Maryland, 21287, United States
-
Oregon Health Sciences University
Portland, Oregon, 97239, United States
-
Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44146, United States
-
Riley Hospital for Children
Indianapolis, Indiana, 46202, United States
-
Seattle Children's Hospital
Seattle, Washington, 98105, United States
-
Stanford University Medical Center
Palo Alto, California, 94304, United States
-
The Minnesota Cystic Fibrosis Center
Minneapolis, Minnesota, 55455, United States
-
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
-
University of Iowa
Iowa City, Iowa, 52242, United States
-
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
-
University of Wisconsin
Madison, Wisconsin, 53792, United States
-
Virginia Commonwealth University
Richmond, Virginia, 23219, United States
-
Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.