New hope for kids with rapid-aging disease: drug combo tested

This study tests a new drug called progerinin, given together with the standard medicine lonafarnib, in 10 children with Hutchinson-Gilford progeria syndrome (a rare disease that causes rapid aging). The goal is to find the best dose and check if the combination is safe and tolerable. Participants either take lonafarnib alone or lonafarnib plus progerinin.