New antibody drug aims to rescue hearts in shock

NCT ID NCT06832722

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests a new drug called procizumab in people with cardiogenic shock, a condition where the heart suddenly can't pump enough blood to vital organs, often leading to death. The drug is designed to block a harmful protein (cDPP3) that rises during shock. About 130 adults with high cDPP3 levels will receive either procizumab or a placebo to check safety and find the best dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charles University Motol University Hospital

    RECRUITING

    Prague, Czechia

    Contact

  • Clinical University Hospital Poznań

    RECRUITING

    Poznan, Poland

    Contact Email: •••••@•••••

  • Département d'anesthésie-réanimation

    NOT_YET_RECRUITING

    Dijon, 21000, France

    Contact

  • Erebouni Mwdical Center

    NOT_YET_RECRUITING

    Yerevan, 0087, Armenia

    Contact

  • General University Hospital in Prague - FVN

    RECRUITING

    Prague, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Górnośląskie Centrum Medyczne w Katowicach / Śląski Uniwersytet Medyczny w Katowicach

    RECRUITING

    Katowice, Poland

    Contact

  • Heart Center Aalst, AZORG

    RECRUITING

    Aalst, Belgium

    Contact

  • Hôpital Pitié Salpêtrière

    NOT_YET_RECRUITING

    Paris, 75651, France

    Contact

  • Institute of Clinical and Experimental Medicine - IKEM

    RECRUITING

    Prague, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • J. Mikulicz Radecki Clinical University Hospital Wrocław

    RECRUITING

    Wroclaw, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lariboisière Hospital AP-HP

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Radboud University Medical Center

    RECRUITING

    Nijmegen, Netherlands

    Contact Email: •••••@•••••

  • Regional University Hospital Nancy - Hopitaux de Brabois

    RECRUITING

    Nancy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Uniersytecki Szpital Kliniczny w Białystoku

    RECRUITING

    Bialystok, Poland

    Contact

  • University Hospital - Dupuytren Limoges

    RECRUITING

    Limoges, France

    Contact Email: •••••@•••••

  • University Hospital Avicenne AP-HP

    RECRUITING

    Bobigny, France

    Contact Email: •••••@•••••

  • University Hospital Lille - Institut Cœur Poumon

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Saint Pierre

    RECRUITING

    Brussels, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital and Medical Faculty of Pilsen

    RECRUITING

    Pilsen, Czechia

    Contact

  • Yerevan medical scientific center

    NOT_YET_RECRUITING

    Yerevan, 0014, Armenia

    Contact

Conditions

Explore the condition pages connected to this study.