Could a daily probiotic protect your gut while traveling abroad?
NCT ID NCT07705659
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This trial investigates whether a probiotic supplement containing two strains of Bifidobacterium longum can help maintain gut health and reduce symptoms like digestive issues, respiratory problems, and poor well-being during short overseas trips (7 days or less). Healthy adults traveling from China to an overseas destination take one sachet of the probiotic or a placebo daily from departure until return. The study measures changes in gut bacteria, immune markers, and self-reported symptoms.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a probiotic supplement containing two strains of Bifidobacterium longum
- What this could lead to
- If it works, this could point toward a simple way to prevent travel-related gut and immune issues.
- What could go wrong
- This is a small early-stage trial with only 40 participants, so results may not apply broadly. The supplement may not outperform a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: 18-65 years, inclusive, with no restriction on gender. 2. Planned short-term round-trip travel from China to an overseas destination, with a total travel duration of no more than 7 days. 3. Volunteers must be able to understand and comply with the study protocol, and provide written informed consent prior to initiation of any study procedures. Exclusion Criteria: 1. Diseases that may affect the evaluation of trial results, including but not limited to immune dysfunction, severe renal/hepatic impairment, severe cardiovascular disease, malignant tumors, acute or chronic infections, etc. 2. Use of probiotic preparations, antibiotics, hormones, immunosuppressants, biological agents, or JAK inhibitors within 4 weeks prior to enrollment. 3. Subjects with confirmed or uncontrolled parasitic infections. 4. ① Patients receiving long-term medication for chronic diseases; ② Patients with severe organic lesions of the thyroid, heart, brain, lungs, kidneys, or musculoskeletal system; ③ Patients with a history of or current psychiatric disorders; ④ Patients on long-term glucocorticoid therapy; ⑤ Patients using growth hormone, γ-aminobutyric acid, lysine, inositol, or vitamin B12. 5. Any uncontrolled, clinically significant laboratory abnormalities that, in the opinion of the investigator, may interfere with the interpretation of study data or the subject's ability to participate in the study. 6. Participation in other clinical intervention studies involving drugs, dietary supplements, probiotics, or prebiotics within the past 4 weeks. 7. Subjects with severe infection or severe trauma as determined by the investigator, or those who have undergone moderate to major surgery within the past month. 8. Known allergy to any components of the probiotic product. 9. Subjects deemed unsuitable for participation in this clinical study by the investigator for any other reason.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.