Could a probiotic during pregnancy help babies grow stronger?
NCT ID NCT07134790
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a probiotic called VE818 can reduce harmful gut bacteria and improve gut health in pregnant women. The trial involves 144 women in Bangladesh, Pakistan, Zambia, and Burkina Faso who are in their first or early second trimester. Participants first take an antibiotic (vancomycin) to clear bad bacteria, then receive either VE818 or a placebo to see if the probiotic helps restore a healthier gut.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- VE818 (a mix of 11 beneficial bacteria) and oral vancomycin
- What this could lead to
- If it works, this could point toward a way to improve gut health in pregnant women, potentially reducing malnutrition and stunting in their babies.
- What could go wrong
- This is an early phase 2 proof-of-concept trial with only 144 participants, so results may not apply broadly. The probiotic may not effectively displace harmful bacteria, and side effects are possible.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique
RECRUITINGBobo-Dioulasso, Burkina Faso
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