Could a probiotic ease histamine intolerance symptoms?
NCT ID NCT07397962
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a probiotic supplement can reduce symptoms of histamine intolerance in adults. Fifty-four participants took either the probiotic or a placebo daily for four weeks. Researchers measured changes in digestive issues, flushing, itching, and headaches to see if the probiotic helped.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Probio Histamed® (a mix of Bifidobacterium and Lactobacillus bacteria)
What this could lead to
If it works, this could point toward a simple, natural way to manage histamine intolerance symptoms like stomach pain, flushing, and headaches.
What could go wrong
This is a small, completed trial with only 54 participants. The results may not apply to everyone, and the probiotic might not work better than a placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Zentrum für klinische Ernährung Stuttgart
Stuttgart, 70599, Germany