Jaw fracture patients may regain sensation with own blood product
NCT ID NCT07319650
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether applying platelet-rich fibrin (PRF) — a concentrate made from a patient's own blood — to the mental nerve during jaw fracture surgery can improve recovery of sensation in the chin and lower lip. 40 people with a broken jaw and numbness will be randomly assigned to receive either standard surgery plus PRF or standard surgery alone. The main outcome is the ability to feel two pinpricks at different distances on the skin, measured before surgery, right after, and at 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- platelet-rich fibrin (PRF)
- What this could lead to
- If it works, this could offer a simple, low-cost way to improve nerve healing after jaw fractures, reducing numbness in the chin and lip.
- What could go wrong
- This is a small, early-stage trial with only 40 people. The benefit may be small or not apply to everyone. PRF is made from the patient's own blood, so risks are low but not zero.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Allama Iqbal Medical College/ Jinnah Hospital Lahore
Lahore, Punjab Province, 54550, Pakistan
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