Jaw fracture patients may regain sensation with own blood product

NCT ID NCT07319650

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether applying platelet-rich fibrin (PRF) — a concentrate made from a patient's own blood — to the mental nerve during jaw fracture surgery can improve recovery of sensation in the chin and lower lip. 40 people with a broken jaw and numbness will be randomly assigned to receive either standard surgery plus PRF or standard surgery alone. The main outcome is the ability to feel two pinpricks at different distances on the skin, measured before surgery, right after, and at 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

platelet-rich fibrin (PRF)

What this could lead to

If it works, this could offer a simple, low-cost way to improve nerve healing after jaw fractures, reducing numbness in the chin and lip.

What could go wrong

This is a small, early-stage trial with only 40 people. The benefit may be small or not apply to everyone. PRF is made from the patient's own blood, so risks are low but not zero.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

jaw fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allama Iqbal Medical College/ Jinnah Hospital Lahore

    Lahore, Punjab Province, 54550, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact