Could a simple pill before endoscopy prevent a painful complication?

NCT ID NCT05252754

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 17 times

Summary

This study tests whether adding an oral drug called tacrolimus before an ERCP procedure can prevent pancreatitis, a painful inflammation of the pancreas that sometimes occurs after the procedure. About 4,800 adults undergoing ERCP will be randomly assigned to receive either the standard preventive treatment (a rectal anti-inflammatory) alone or that treatment plus tacrolimus. The goal is to see if the combination reduces the number of people who develop pancreatitis after the procedure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Apollo Multispecialty Hospitals,

    NOT_YET_RECRUITING

    Kolkata, West Bengal, 700054, India

    Contact Email: •••••@•••••

  • Asian Institute of Gastroenterology

    RECRUITING

    Hyderabad, Andhra Pradesh, 500082, India

    Contact Email: •••••@•••••

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Post Graduate Institute of Medical Education and Research

    NOT_YET_RECRUITING

    Chandigarh, 160012, India

    Contact Email: •••••@•••••

  • Singapore General Hospital

    NOT_YET_RECRUITING

    Singapore, 169608, Singapore

    Contact Email: •••••@•••••

Conditions

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