Simpler HIV pill combo shows promise in protecting newborns

NCT ID NCT02738502

First seen Apr 30, 2026 · Last updated May 12, 2026 · Updated 3 times

Summary

This study tested whether pregnant women with well-controlled HIV could switch to a simpler two-drug regimen (darunavir/ritonavir) instead of their usual three-drug cocktail, to prevent passing the virus to their babies. 91 women joined the study, and the main goal was to see if the virus stayed undetectable near delivery. The approach aimed to reduce medication exposure while still protecting the newborn.

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Contacts and locations

Locations

  • CH Victor Dupouy

    Argenteuil, 95100, France

  • CHU Archet 1

    Nice, 06202, France

  • CHU Rennes Hôpital Pontchaillou

    Rennes, 35000, France

  • CHU Toulouse

    Toulouse, 31059, France

  • CHU de Perpignan

    Perpignan, 66046, France

  • Groupe hospitalier Cochin-Broca- Hôtel Dieu

    Paris, 75014, France

  • Groupe hospitalier Pellegrin

    Bordeaux, 33000, France

  • HEGP

    Paris, 75015, France

  • Hôpital Antoine Béclère

    Clamart, 92140, France

  • Hôpital Armand Trousseau

    Paris, 75012, France

  • Hôpital Bichat - Claude Bernard

    Paris, 75018, France

  • Hôpital Bicêtre

    Le Kremlin-Bicêtre, 94275, France

  • Hôpital Foch

    Suresnes, 92151, France

  • Hôpital Jean Verdier

    Bondy, 93140, France

  • Hôpital Lariboisiere

    Paris, 75010, France

  • Hôpital Louis Mourier

    Colombes, 92700, France

  • Hôpital Necker Enfant malades

    Paris, 75015, France

  • Hôpital Saint André

    Bordeaux, 33075, France

  • Hôpital Sud Francilien

    Corbeil-Essonnes, 91106, France

  • Hôpital Tenon

    Paris, 75020, France

  • Hôpital de la croix Rousse

    Lyon, 69307, France

  • Hôpital la Pitié Salpétrière

    Paris, 75013, France

  • Hôtel Dieu

    Nantes, 44093, France

Conditions

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