New catheter lock may cut blockages in kids on long-term nutrition

NCT ID NCT05879835

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if a 4% tetrasodium EDTA solution is better than the standard heparin lock at preventing central line blockages in children with intestinal failure who need long-term nutrition through a vein. About 124 children from multiple hospitals will take part. The goal is to reduce the need for extra procedures to fix blocked catheters and to see if it also lowers infection rates.

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Conditions

The condition(s) this trial relates to.

chronic intestinal failure Hyperphagia Intestinal Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

  • Cook Children's Health Care System

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

  • Nyph/Cumc

    RECRUITING

    New York, New York, 10032, United States

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

  • University of Nebraska Medical Center

    NOT_YET_RECRUITING

    Omaha, Nebraska, 68198, United States

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