New catheter lock may cut blockages in kids on long-term nutrition
NCT ID NCT05879835
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if a 4% tetrasodium EDTA solution is better than the standard heparin lock at preventing central line blockages in children with intestinal failure who need long-term nutrition through a vein. About 124 children from multiple hospitals will take part. The goal is to reduce the need for extra procedures to fix blocked catheters and to see if it also lowers infection rates.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Cook Children's Health Care System
RECRUITINGFort Worth, Texas, 76104, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
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Nyph/Cumc
RECRUITINGNew York, New York, 10032, United States
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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University of Nebraska Medical Center
NOT_YET_RECRUITINGOmaha, Nebraska, 68198, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Muscle loss in intestinal failure: could a simple protein and workout combo turn the tide?
- Measuring hidden energy needs: a clue to better nutrition for gut failure patients
- Kids off IV nutrition: are they thriving?
- Baking soda in catheters may cut infections in kids with gut failure
- Tiny sensor reveals hidden blood sugar swings in fragile infants
- Could a simple lock solution prevent dangerous line infections in kids?