Old drug, new trick: vancomycin may stop c. diff before it starts
NCT ID NCT07221708
First seen Jun 25, 2026 · Last updated Jul 30, 2026 · Updated 4 times
Summary
This study tests whether taking oral vancomycin alongside other antibiotics can prevent Clostridioides difficile infection (C. diff) in people aged 65 and older. Participants are randomly assigned to receive either vancomycin or standard care. The goal is to see if the drug reduces the number of new C. diff cases.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oral vancomycin
- What this could lead to
- If it works, this could provide a simple way to prevent C. diff infections in high-risk older patients taking antibiotics.
- What could go wrong
- This is an early-to-mid stage trial with only 200 participants. The drug may not prevent infection and could promote antibiotic resistance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Maryland Baltimore Washington Medical Center
Glen Burnie, Maryland, 21061, United States