New blood clot pill for knee surgery patients falls short in early trial

NCT ID NCT05203705

First seen Nov 17, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tested a new oral blood thinner (SHR2285) against a standard injection (enoxaparin) to prevent dangerous blood clots after total knee replacement. The trial planned to enroll 64 adults aged 40-75, but was terminated early. The goal was to see if the pill was as safe and effective as the injection in preventing clots and major bleeding.

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Contacts and locations

Locations

  • Perking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

Conditions

Explore the condition pages connected to this study.