Foreskin tissue offers new hope for complex ureteral repair

NCT ID NCT07408050

ENROLLING_BY_INVITATION Disease control Sponsor: Ruibao chen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study tests a new surgical technique that uses a piece of foreskin (from circumcision) to repair complex ureteral strictures—narrowing of the tube that carries urine from the kidney to the bladder. The trial will enroll 50 men who cannot be treated with standard surgery. The goal is to see if this graft can safely restore urine flow and protect kidney function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
preputial graft (foreskin tissue used as a graft for ureteral reconstruction)
What this could lead to
If successful, this could provide a safe, minimally invasive surgical option for repairing complex ureteral strictures using tissue that is normally discarded.
What could go wrong
This is a small, early-stage study (50 participants) with no control group. The procedure may not work for all types of strictures, and risks include graft failure or complications from surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China