Botox shots before hernia repair may reduce need for major surgery
NCT ID NCT07349628
First seen Jan 28, 2026 · Last updated Jun 22, 2026 · Updated 21 times
Summary
This study looked at 32 people with complex incisional hernias who received Botox injections into their abdominal wall muscles before surgery. The idea was that relaxing the muscles would make it easier to close the hernia without more extensive cutting. Researchers measured how often the hernia could be closed with a standard technique and tracked complications. The results suggest preoperative Botox may help, but the study was small and observational, so more research is needed.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aslnapoli2Nord
Naples, Naples, 80131, Italy
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
botulinum toxin A (Botox)
What this could lead to
If it works, this could make complex hernia repairs safer and less invasive by relaxing the abdominal muscles beforehand.
What could go wrong
This is a small observational study with only 32 patients and no control group, so results may not apply to everyone. Botox is temporary and may not help all hernia types.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.