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Could air pollution before birth raise ADHD risk? new brain scan study aims to find out

NCT ID NCT05368493

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: New York State Psychiatric Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether air pollution exposure before birth is linked to ADHD risk in Puerto Rican children. Researchers will use brain scans (MRI) in 182 kids aged 6-11 to examine brain areas tied to attention. They also want to see if inflammation during pregnancy or sleep problems in childhood play a role. The goal is to find early, changeable factors that could help prevent ADHD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help identify early, modifiable factors (like inflammation or sleep) that link pollution to ADHD, pointing toward prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It may find no clear link, or results may not apply to other populations. Brain scans are exploratory.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neurodevelopmental disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEURODEVELOPMENTAL DISORDERS POLLUTION; EXPOSURE

Contacts and locations

Locations

  • New York State Psychiatric Institute

    New York, New York, 10032, United States

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