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Personality traits may forecast Post-Surgery agitation

NCT ID NCT07775768

Knowledge-focused Sponsor: Hongjiao Xu Source: ClinicalTrials.gov ↗

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Cancelled before anyone took part.

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First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This study is testing whether a simple personality-based score, called the fBFI-ENO score, can predict which patients will experience emergence delirium—a state of confusion and restlessness—when waking up from general anesthesia. The score is based on three personality traits: extraversion, neuroticism, and openness. Researchers will follow 880 adults undergoing elective non-cardiac surgery with general anesthesia to see if the score's predictive ability holds across different genders, ages, and types of surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the score proves reliable, it could help doctors identify patients at higher risk of post-anesthesia restlessness, allowing for tailored care and prevention strategies.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The score's accuracy may vary across different patient groups, and it may not be generalizable to all surgical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 880 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for non-cardiac surgery, undergoing general anesthesia with endotracheal intubation, aged 18 years or older, and with ASA classification of I-III.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * General anesthesia with tracheal intubation is planned for elective non-cardiac surgery. * Age ≥18 years old, gender not limited; * American Society of Anesthesiologists (ASA) classification I-III; * Voluntarily participate in this project and sign the informed consent form. Exclusion Criteria: * The anesthesia method was temporarily changed to local anesthesia, regional anesthesia or intravenous anesthesia; * There was a clear cognitive dysfunction before the surgery (MMSE score lower than the qualified standard corresponding to the educational level: illiterates ≤ 17 points; primary school level ≤ 20 points; secondary (technical secondary) school level: ≤ 22 points; university (college) and above level: ≤ 23 points) or communication difficulties; * There is a history of mental illness or long-term use of psychotropic drugs; * It is expected to be transferred to the intensive care unit (ICU) immediately after the surgery or requires a sedated state and cannot undergo standard assessment in the PACU; * Has participated in or is currently participating in other clinical trials within 1 month; * The investigator determines that there are other circumstances that are not suitable for participating in this trial.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Emergence delirium, anesthesia

How to take part

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  1. The official record

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