New hope for tough leukemia: precision drug combo trial launches
NCT ID NCT07522801
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether personalized drug combinations can help people with relapsed or treatment-resistant T-cell acute lymphoblastic leukemia (T-ALL). Researchers will assign patients to one of several targeted therapies based on lab tests. The main goal is to see if these treatments can achieve complete remission within three months. About 93 participants aged 15 and older will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Venetoclax, Tofacitinib, Everolimus, Enrylaze
What this could lead to
If successful, this could offer a new treatment option for patients with hard-to-treat T-cell leukemia, potentially leading to better remission rates.
What could go wrong
This is an early phase 2 trial with only 93 participants, so results may not apply to everyone. The drug combinations can cause side effects, and the study hasn't started recruiting yet.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Contact
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Locations
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APHM Conception
Marseille, France
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CH Victor Dupouy
Argenteuil, France
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CH cote basque
Bayonne, France
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CHRU Hopital Bretonneau
Tours, France
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CHRU Nancy
Vandœuvre-lès-Nancy, France
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CHU Amiens Picardie
Amiens, France
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CHU Besancon
Besançon, France
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CHU Caen
Caen, France
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CHU Clermont Ferrand
Clermont-Ferrand, France
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CHU Dijon Bourgogne
Dijon, France
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CHU Henri Mondor
Créteil, France
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CHU Lille
Lille, France
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CHU Nantes
Nantes, France
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CHU Nice
Nice, France
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CHU Saint Etienne
Saint-Priest-en-Jarez, France
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CHU Toulouse
Toulouse, France
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CHU de Brest
Brest, France
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CHU de Grenoble
Grenoble, France
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CHU de Limoges
Limoges, France
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CHU de Nîmes
Nîmes, France
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CHU de Poitiers
Poitiers, France
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CHU de Reims
Reims, France
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CHV
Versailles, France
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Centre Henri Becquerel
Rouen, France
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Centre Hospitalier Regional Metz Thionville
Metz, France
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Centre Hospitalier Sud Francilien
Corbeil-Essonnes, France
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Centre Hospitalier d'Avignon
Avignon, France
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Centre Hospitalier de Dunkerque
Dunkirk, France
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Centre Hospitalier de Perpignan
Perpignan, France
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Centre Hospitalier de Versailles
Le Chesnay, France
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Centre Hospitalier du Pays d'Aix
Aix-en-Provence, France
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Chu Angers
Angers, France
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Chu Orléans
Orléans, France
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Clinique du Parc
Castelnau-le-Lez, France
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Czech medical chamber
Prague, Czechia
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Erasmus Medical Center
Rotterdam, Netherlands
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GHRMSA - Hopital E Muller
Mulhouse, France
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HIA Percy
Clamart, France
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Hematologist at Hospital Universitario Donostia
San Sebastián, Spain
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Hopital Annecy Genevois
Épagny, France
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Hopital Armand Trousseau
Paris, France
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Hopital Avicenne
Bobigny, France
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Hopital Cochin
Paris, France
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Hopital Gerneral Universitario Morales Meseguar
Murcia, Spain
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Hopital Haut Leveque
Bordeaux, France
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Hopital Lyon Sud
Lyon, France
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Hopital Necker Enfants Malades
Paris, France
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Hopital Pitié Salpêtrière
Paris, France
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Hopital Pontchaillou
Rennes, France
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Hopital Robert Debré
Paris, France
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Hopital Saint Antoine
Paris, France
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Hopital Saint Eloi CHU Montpellier
Montpellier, France
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Hopital Saint Louis
Paris, France
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Hopital Saint Louis
Paris, France
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Hopital Victor Provo
Roubaix, France
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Hospital General Universitario Gregorio Marnon
Madrid, Spain
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Hospital Universitario La Fe
Valencia, Spain
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Hospital Universitario Marques de Valdecilla
Santander, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, Spain
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Hospital Universitario de Salamanca
Salamanca, Spain
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Insitut Catala d'Oncologia Badalona
Barcelona, Spain
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Institut Gustave Roussy
Villejuif, France
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Institut Paoli-Calmettes
Marseille, France
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Universidad de Sevilla Facultad de Medicina
Seville, Spain
Contact
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University Hospital Brno
Brno, Czechia
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University Medical Center Utrecht
Utrecht, Netherlands
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Universtatsklinikum Frankfurt Med. Klinik II
Frankfurt, Germany
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Vall D'Hebron University Hospital
Barcelona, Spain
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Wroclaw Medical University
Wroclaw, Poland
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Contact