Could a fizzy fiber drink soothe the gut woes of Weight-Loss drugs?
NCT ID NCT07744360
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study tests whether drinking a prebiotic soda—a fizzy drink with added fiber—can ease the nausea, constipation, and other stomach issues that often come with GLP-1 weight-loss medications like semaglutide and tirzepatide. About 80 adults currently taking these drugs and experiencing gut side effects will be randomly assigned to drink the soda daily or stick with their usual fluids. Researchers will track changes in gastrointestinal symptoms, stool habits, quality of life, and diet to see if the soda offers relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Prebiotic soda (6 g dietary fiber per 12 fl oz serving)
- What this could lead to
- If it works, this could offer a simple, drug-free way to manage common gut side effects of GLP-1 weight-loss medications, potentially improving comfort and quality of life for users.
- What could go wrong
- This is a small pilot study, so results may not apply broadly. The soda's fiber could also worsen symptoms in some people, and the open-label design means participants know what they're drinking, which can bias results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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People Science
Los Angeles, California, 90034, United States
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