New pill aims to tame debilitating skin itch in Final-Stage trial

NCT ID NCT06516952

Recruiting now Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an oral medication called povorcitinib can reduce severe itching and heal skin lesions in people with prurigo nodularis, a chronic skin condition. About 330 adults with moderate-to-severe symptoms who haven't responded well to other treatments will receive either the drug or a placebo for 24 weeks. Researchers will measure improvements in itch intensity, skin appearance, and quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Aachen University Hospital
NOT_YET_RECRUITING

Aachen, 52074, Germany
Alpha Research-Lucere Dermatology and Laser Clinic
RECRUITING

Edmonton, Alberta, T6X 0N9, Canada
Amsterdam Universitair Medisch Centrum, Locatie Amsterdam Medisch Centrum
COMPLETED

Amsterdam, 1105 AZ, Netherlands
Aou Universita Della Campania Luigi Vanvitelli, Azienda Ospedaliero Universitaria Federico Ii Di Nap
RECRUITING

Naples, 80131, Italy
Azienda Ospedaliera Di Perugia
RECRUITING

Perugia, 06129, Italy
Azienda Ospedaliero Universitaria Pisana - Ospedale S. Chiara
RECRUITING

Pisa, 56126, Italy
Azienda Ospedaliero-Universitaria Policlinico Vittorio Emanuele Ospedale Gaspare Rodolico Di Catania
RECRUITING

Catania, 95123, Italy
Azienda Sanitaria Locale 1 (Asl 1) - Ospedale Regionale San Salvatore
RECRUITING

L’Aquila, 67100, Italy
Banner - University Medicine Multispecialty Services Clinic
RECRUITING

Tucson, Arizona, 85718, United States
Burke Pharmaceutical Research
RECRUITING

Hot Springs, Arkansas, 71913, United States
Cabinet Medical- Chemin de Paradis
NOT_YET_RECRUITING

Martigues, 13500, France
Cahaba Dermatology
RECRUITING

Birmingham, Alabama, 35244, United States
Catholic University of the Sacred Heart
RECRUITING

Rome, 00168, Italy
Cedic - Centro de Investigacion Clinica
RECRUITING

Buenos Aires, C1060ABN, Argentina
Center For Clinical Studies
RECRUITING

Webster, Texas, 77598, United States
Center For Medical Dermatology and Immunology Research
RECRUITING

Chicago, Illinois, 60657, United States
Centre Hospitalier Universitaire de Nantes (Chu de Nantes) - Hopital Hotel Dieu
RECRUITING

Nantes, 44093, France
Centre de Recherche Dermatologique de Quebec
RECRUITING

Québec, Quebec, G1V4X7, Canada
Centre de Recherche Saint-Louis
RECRUITING

Québec, Quebec, G1W 4R4, Canada
Centricity Research Columbus
RECRUITING

Columbus, Ohio, 43213, United States
Centricity Research London Victoria Multispecialty
RECRUITING

London, Ontario, N6A 2C2, Canada
Centro de Investigaciones Medicas Mar Del Plata
RECRUITING

Mar del Plata, B7600FYK, Argentina
Centrum Badan Klinicznych, Jagiellonskie Centrum Innowacji Sp.Z.O.O.
RECRUITING

Krakow, 30-348, Poland
Centrum Medyczne Evimed
RECRUITING

Warsaw, 02-625, Poland
Charite Universitatsmedizin Berlin
RECRUITING

Berlin, 12203, Germany
Chicago Cosmetic Surgery and Dermatology
COMPLETED

Chicago, Illinois, 60654, United States
Chu Paris-Gh St-Louis Lariboisiere F.Widal Hopital Saint-Louis
RECRUITING

Paris, 75010, France
Clinical Research Centre - Cast
RECRUITING

Chieti, 66013, Italy
Clinical Research Group Sp. Z.O.O
RECRUITING

Warsaw, 01-142, Poland
Conexa Investigacion Clinica S.A.
RECRUITING

Buenos Aires, 01012, Argentina
Dermaceum Centrum Badan Klinicznych
RECRUITING

Wroclaw, 53-613, Poland
Dermatology Research Associates
RECRUITING

Los Angeles, California, 90045, United States
Dermatology Research Institute
RECRUITING

Calgary, Alberta, T2J 7E1, Canada
Dermatology Specialists Research Ds Research Indiana Location
RECRUITING

Clarksville, Indiana, 47129, United States
Dermatology Treatment and Research Center
RECRUITING

Dallas, Texas, 75230, United States
Dermeffects
RECRUITING

London, Ontario, N6H 5L5, Canada
Diagnostic-Consultative Center Aleksandrovska Eood
RECRUITING

Sofia, 01431, Bulgaria
Diagnostic-Consultative Center Ascendent Eood
RECRUITING

Sofia, 01202, Bulgaria
Diagnostic-Consultative Centre Pulmed Eood
RECRUITING

Plovdiv, 04002, Bulgaria
Diamond Clinic Sp. Z O.O.
RECRUITING

Krakow, 31-559, Poland
Driven Research Llc
RECRUITING

Coral Gables, Florida, 33134, United States
Dsc Clinic Buochs
RECRUITING

Buochs, 06374, Switzerland
Euromedicare Przychodnia Specjalistyczna We Wroclawiu Pilczycka
RECRUITING

Wrocaw, 54144, Poland
Fachklinik Bad Bentheim
RECRUITING

Bad Bentheim, 48455, Germany
Frontier Dermatology
RECRUITING

Mill Creek, Washington, 98012, United States
Ghrmsa Hopital Emile Muller
COMPLETED

Mulhouse, 68100, France
Gyncentrum Sp. Z O.O., Nzoz Holsamed- Oddzial Libero
RECRUITING

Katowice, 40-600, Poland
Hamzavi Dermatology
COMPLETED

Fort Gratiot, Michigan, 48059, United States
Hautzentrum Friedrichshain Studien
RECRUITING

Berlin, 10247, Germany
Hopital Larrey
RECRUITING

Toulouse, 31400, France
Hopital Prive D Antony
RECRUITING

Antony, 92160, France
Hopitaux Drome Nord - Site de Romans Sur Isere
RECRUITING

Romans-sur-Isère, 26102, France
Hospital Morvan
RECRUITING

Brest, 29200, France
Illinois Dermatology Institute the Chicago Loop
RECRUITING

Chicago, Illinois, 60602, United States
Inselspital Bern
RECRUITING

Bern, 03010, Switzerland
Instituto Especialidades de La Salud Rosario - Clinica Del Torax
RECRUITING

Rosario, S2000, Argentina
Instituto de Investigaciones En Alergia Y Enfermedades Respiratorias (Inaer)
RECRUITING

Buenos Aires, C1425BEN, Argentina
Instituto de Neumonologia Y Dermatologia
NOT_YET_RECRUITING

Buenos Aires, C1425BEA, Argentina
International Clinical Research Tennessee Llc
COMPLETED

Murfreesboro, Tennessee, 37130, United States
Investigaciones Reumatologicas Tucuman S.R.L.
RECRUITING

San Miguel de Tucumán, T4000AXL, Argentina
Irccs Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy
Jeonbuk National University Hospital
RECRUITING

Jeonju, 54907, South Korea
Klinika Ambroziak Sp. Z O.O.
RECRUITING

Warsaw, 02-953, Poland
Klinikum Dortmund Ggmbh
RECRUITING

Dortmund, 44137, Germany
Konkuk University Medical Center
COMPLETED

Seoul, 05030, South Korea
Korea University Ansan Hospital
RECRUITING

Ansan-si, 15355, South Korea
Laser Clinic
RECRUITING

Szczecin, 70-332, Poland
Maxima Medisch Centrum
COMPLETED

Veldhoven, 5504 DB, Netherlands
Mazowieckie Centrum Badan Klinicznych
RECRUITING

Pruszków, 05-800, Poland
Medconsult Pleven
RECRUITING

Pleven, 05800, Bulgaria
Medical Center Medconsult Pleven
RECRUITING

Lovech, 05500, Bulgaria
Medical Center Prolet Eood
RECRUITING

Rousse, 07000, Bulgaria
Medical Center Unimed Eood
RECRUITING

Sevlievo, 05400, Bulgaria
Medical University Graz University Clinic For Dermatology and Venerology
RECRUITING

Graz, 08036, Austria
Medisearch Clinical Trials
RECRUITING

Saint Joseph, Missouri, 64506, United States
Montefiore Medical Center
COMPLETED

East Syracuse, New York, 13057, United States
Niepubliczny Zaklad Opieki Zdrowotnej Med-Laser
RECRUITING

Lublin, 20-406, Poland
Niepubliczny Zaklad Opieki Zdrowotnej Specjalistyczny Osrodek Dermatologiczny Dermal
RECRUITING

Bialystok, 15-453, Poland
North York Research Inc.
RECRUITING

Toronto, Ontario, M2N 3A6, Canada
Northridge
RECRUITING

Northridge, California, 91325, United States
Northshore University Healthsystem
COMPLETED

Skokie, Illinois, 60077, United States
Nzoz Gyncentrum - Oddzial Warszawa
RECRUITING

Warsaw, 00-124, Poland
Oakland Hills Dermatology
RECRUITING

Auburn Hills, Michigan, 48326, United States
Park Dermatology
RECRUITING

Sherwood Park, Alberta, T8H 0P1, Canada
Premier Dermatology Clinical Trials Institute At Northwest Arkansas
COMPLETED

Fayetteville, Arkansas, 72703, United States
Presidio Ospedaliero Firenze Centro Piero Palagi
WITHDRAWN

Florence, 50125, Italy
Pro Familia Altera Sp. Z O.O.
COMPLETED

Katowice, 40-648, Poland
Pusan National University Hospital (Pnuh)
RECRUITING

Busan, 49241, South Korea
Pusan National University Yangsan Hospital
RECRUITING

Busan, 50612, South Korea
Rao Dermatology
RECRUITING

Edmonton, Alberta, T6G 1C3, Canada
Rendon Center the Dermatology and Aesthetic Center
RECRUITING

Boca Raton, Florida, 33486, United States
Research Institute of the Southeast, Llc
RECRUITING

West Palm Beach, Florida, 33401, United States
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Sima Recherche
RECRUITING

Verdun, Quebec, H4G 3E7, Canada
Simcoderm Medical and Surgical Dermatology Centre
RECRUITING

Barrie, Ontario, L4M 7G1, Canada
Skin Center Dermatology Group
RECRUITING

New York, New York, 10956, United States
Skin Health
RECRUITING

Cobourg, Ontario, K9A 0Z4, Canada
Skin Physicians
RECRUITING

Edmonton, Alberta, T6W 4V4, Canada
Skinsense Medical Research
RECRUITING

Saskatoon, Saskatchewan, S7K 2C1, Canada
Somerset Skin Centre
COMPLETED

Troy, Michigan, 48084, United States
Soon Chun Hyang University Bucheon Hospital
RECRUITING

Bucheon-si, 14584, South Korea
Stony Brook Dermatology Associates
RECRUITING

Stony Brook, New York, 11790, United States
Sweetwater Dermatology
RECRUITING

Sugar Land, Texas, 77479, United States
The Catholic University of Korea, Incheon St. Mary'S Hospital
RECRUITING

Incheon, 21431, South Korea
The University of New Mexico Unm Health Sciences Center Hsc
RECRUITING

Albuquerque, New Mexico, 87131, United States
Toronto Research Centre
RECRUITING

Toronto, Ontario, M3H 5Y8, Canada
Universitaets-Hautklinik Eberhard-Karls-Universitaet Tuebingen
RECRUITING

Tübingen, 72076, Germany
Universitaetsklinik Und Poliklinik Fuer Dermatologie Und Venerologie
RECRUITING

Halle, 06120, Germany
Universitaetsklinikum Giessen Und Marburg Gmbh
RECRUITING

Marburg, 35043, Germany
Universitaetsklinikum Hamburg-Eppendorf
RECRUITING

Hamburg, 20246, Germany
Universitaetsklinikum Leipzig
RECRUITING

Leipzig, 04103, Germany
Universitaetsklinikum Schleswig-Holstein (Uksh) - Campus Luebeck
RECRUITING

Lübeck, 23538, Germany
Universitaetsmedizin Der Johannes - Gutenberg Universitaet Mainz
RECRUITING

Mainz, 55131, Germany
Universitatsklinik Heidelberg
RECRUITING

Heidelberg, 69115, Germany
Universitatsspital Zurich
RECRUITING

Zurich, 08091, Switzerland
University of Miami Miller School of Medicine
RECRUITING

Miami, Florida, 33136, United States
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-214, Poland
Uoc Dermatologia Ospedale Maggiore Policlinico, Fondazione Irccs Ca' Granda
RECRUITING

Milan, 20122, Italy
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Wiener Krankenanstaltenverbund, Krankenhaus Hietzing Mit Neurologischem Zentrum Rosenhugel
RECRUITING

Vienna, 01130, Austria
Wright State Physicians Health Center
RECRUITING

Dayton, Ohio, 45324, United States

Conditions

Explore the condition pages connected to this study.

PRURIGO NODULARIS