Hope dashed: drug trial for Post-COVID racing heart stopped early

NCT ID NCT06524739

First seen Apr 13, 2026 · Last updated Jun 15, 2026 · Updated 10 times

Summary

This study tested a drug called IgPro20 (HIZENTRA) to see if it could help people with post-COVID POTS, a condition that causes a rapid heart rate and dizziness when standing. The trial was stopped early after enrolling only 16 adults. The goal was to see if the drug could reduce symptoms and improve daily life, but results are limited due to early termination.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Arkansas Cardiology Clinic - Little Rock

    Little Rock, Arkansas, 72205, United States

  • Bateman Horne Center

    Salt Lake City, Utah, 84102, United States

  • Bernstein Clinical Research Center

    Cincinnati, Ohio, 45236, United States

  • Center for Complex Neurology, EDS & POTS

    Phoenix, Arizona, 85006, United States

  • Ciussse-Chus

    Sherbrooke, J1H 5N4, Canada

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Dysautonomia Clinic

    Buffalo, New York, 14221, United States

  • Hightower Clinical

    Oklahoma City, Oklahoma, 73134, United States

  • Hope Research Network

    Miami, Florida, 33166, United States

  • Johns Hopkins Bayview Medical Center PMR

    Baltimore, Maryland, 21224, United States

  • LSU Health Sciences Center

    New Orleans, Louisiana, 70112, United States

  • Libin Cardiovascular Institute University of Calgary

    Calgary, T2N 4Z6, Canada

  • Mass General Brigham (Massachusetts General Hospital)

    Belmont, Massachusetts, 02478, United States

  • Mayo Clinic Arizona

    Scottsdale, Arizona, 85259, United States

  • McGill University Health Centre

    Québec, H4A 3J1, Canada

  • Metrodora Institute

    West Valley City, Utah, 84119, United States

  • NYU Langone Health South Shore Neurologic Associates

    Patchogue, New York, 11772, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Penn Presbyterian Medical Center

    Philadelphia, Pennsylvania, 19104, United States

  • Profound Research LLC at Millennium Affiliated Physicians

    Farmington Hills, Michigan, 48334, United States

  • Prolato Clinical Research Center

    Houston, Texas, 77054, United States

  • Sunbeam Clinical Research

    McKinney, Texas, 75069, United States

  • UC San Diego Health

    La Jolla, California, 92037, United States

  • UT Austin Dell Medical School

    Austin, Texas, 78712, United States

  • University Hospital Cleveland Medical Center

    Cleveland, Ohio, 44195, United States

  • University of Alabama Hospital at Birmingham

    Birmingham, Alabama, 35294-1152, United States

  • University of Alberta Hospital

    Edmonton, T6G 2B7, Canada

  • University of Texas Health Science Center

    San Antonio, Texas, 78229, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of california Irvine

    Orange, California, 92868, United States

  • VCU Health

    Richmond, Virginia, 23219, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Velocity Clinical Research - Hampton

    Hampton, Virginia, 23666, United States

  • Velocity Clinical Research - Lincoln

    Lincoln, Nebraska, 68510, United States

  • Velocity Clinical Research - Union

    Union, South Carolina, 29379, United States

  • Velocity Clinical Research, Metairie

    New Orleans, Louisiana, 70119, United States

  • Velocity Clinical Research, Savannah

    Savannah, Georgia, 31406, United States

  • Well Pharma Medical Research, Corp

    Miami, Florida, 33173, United States

Conditions

The condition(s) this trial relates to.

postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.