Can a sugar pill make you happier? scientists study expectation effects on emotions

NCT ID NCT07615530

First seen May 29, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study looks at how positive expectations—like thinking you received a helpful treatment—can change how your brain processes emotions. Healthy adults will receive a saline nasal spray labeled as either oxytocin or saline on different days. Researchers will measure mood, brain activity (EEG), and eye movements while participants view emotional faces. The goal is to understand the basic mechanisms behind placebo effects in emotions, which could inform future treatments for depression and anxiety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Medical Center Hamburg-Eppendorf, Institute of Systems Neuroscience

    Hamburg, Free and Hanseatic City of Hamburg, 20251, Germany

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help develop new psychological therapies for mood disorders by understanding how expectations shape emotions.

What could go wrong

This is a small, early-stage study in healthy volunteers, not patients. It tests basic mechanisms, not a treatment, so real-world applications are uncertain.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.