Can a sugar pill make you happier? scientists study expectation effects on emotions

NCT ID NCT07615530

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how positive expectations—like thinking you received a helpful treatment—can change how your brain processes emotions. Healthy adults will receive a saline nasal spray labeled as either oxytocin or saline on different days. Researchers will measure mood, brain activity (EEG), and eye movements while participants view emotional faces. The goal is to understand the basic mechanisms behind placebo effects in emotions, which could inform future treatments for depression and anxiety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help develop new psychological therapies for mood disorders by understanding how expectations shape emotions.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. It tests basic mechanisms, not a treatment, so real-world applications are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Medical Center Hamburg-Eppendorf, Institute of Systems Neuroscience

    Hamburg, Free and Hanseatic City of Hamburg, 20251, Germany