Can a simple pill shield transplant patients from deadly fungal infections?
NCT ID NCT04725942
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether the drug posaconazole can prevent fungal lung infections in people who have had a stem cell transplant. 360 patients took the drug for 90 days after their transplant. Researchers checked drug levels in the blood and tracked how many patients got infections. The goal was to find the right dose to keep patients safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- posaconazole tablets
- What this could lead to
- If successful, this could confirm that posaconazole is a safe and effective way to prevent serious fungal lung infections in stem cell transplant patients.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less definitive. The drug may not prevent all infections and could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences
Tianjin, China
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Shanxi Bethune Hospital
Taiyuan, China
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The Second Hospital of Hebei Medical University
Shijia Zhuang, China
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Tianjin Medical University Cancer Institute and Hospital
Tianjin, China