Can a portable MRI see brain lesions as well as big machines?
NCT ID NCT07296263
First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times
Summary
This study looks at whether a portable MRI machine, combined with a standard contrast dye, can clearly show brain lesions like tumors or infections. About 85 adults with known or suspected brain lesions will get a scan before and after receiving the dye. The goal is to see if portable MRI can provide useful images, which could help patients who can't easily access traditional MRI scanners.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Gadolinium-based contrast agent
- What this could lead to
- If successful, this could make high-quality brain imaging more accessible using portable MRI machines, especially for patients who cannot use traditional scanners.
- What could go wrong
- This is an early-stage study focused on image quality, not treatment. The portable MRI has lower magnetic strength than standard machines, so it may not detect all lesions clearly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 85 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2025
- Expected to finish
-
Oct 2026
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria To be eligible to participate in this study, an individual must meet all the following criteria: * Age ≥18 years Clinical indication of suspected or known brain lesion(s) with focal blood-brain barrier disruption. Preferably, at least one previously documented brain lesion with focal areas of blood-brain barrier disruption categorizable as: * intra-axial tumor(s) * extra-axial tumor(s) * infection/inflammatory lesion(s) * Cleared for portable MRI (pMRI) and intravenous GBCA administration per site policy. * Adequate peripheral venous access for contrast injection. * Able to provide informed consent and comply with brief supine imaging (pre- and post-contrast) Exclusion Criteria Participants will be excluded if they meet any of the following criteria: * Metallic clips or devices in the brain or eye. * Body weight greater than 200 kg. * Inability to fit or be positioned appropriately within the Swoop® Portable MR Imaging® System. * Inability to remain still or lie flat during the imaging period. * Not cleared for GBCA administration due to known hypersensitivity, allergy, or contraindication. * Severe renal impairment (eGFR \< 30 mL/min/1.73 m²) or acute kidney injury. * History of severe reaction to any gadolinium-based contrast agent. * GBCA administration within the prior 48 hours (or alternative clearance window defined by institution) * Known or suspected pregnancy at the time of imaging. * Any medical or behavioral condition that, in the investigator's judgment, would make participation unsafe or interfere with study completion. Subjects may be selectively enrolled or excluded to ensure inclusion of radiology finding subgroups and GBCA agents.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Extra-axial tumors are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
6 sites. The list below names each one and where it is.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
CHRISTUS Trinity Mother Frances Health System
Tyler, Texas, 75701, United States
-
Dent Neurologic Institute
Amherst, New York, 14226, United States
-
Jefferson Abington Hospital
Abington, Pennsylvania, 19001, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Neurology of Central Florida Research Center
Altamonte Springs, Florida, 32714, United States
-
Texas Neurology
Dallas, Texas, 75206, United States