Do four or more medications throw older adults off balance?

NCT ID NCT07816276

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First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers at Ondokuz Mayıs University are studying whether taking four or more medications is linked to worse balance, higher fall risk, and lower thinking skills in older adults living in nursing homes. The study compares 50 residents aged 60 and older in Samsun, Turkey, split into a polypharmacy group and a control group taking fewer or no medications. Participants complete walking, balance, thinking, vestibular, and hearing tests to see how medication use relates to these outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers find a link between multiple medications and worse balance or thinking, this could shape how doctors review and reduce medication lists for older adults in nursing homes.
What could go wrong
The study only observes 50 nursing home residents in one city, so it cannot prove that medications cause balance or memory problems. Other factors, such as age and existing health conditions, may explain any differences.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of individuals aged 60 years and older living in nursing homes in Samsun. Participants were divided into two groups according to medication use: a polypharmacy group and a control group. All participants were able to walk independently, communicate verbally, and complete the study assessments.

Ages

60 to 99 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals aged 60 years and older * Individuals living in nursing homes in Samsun * Individuals in the polypharmacy group using the defined number of medications and individuals in the control group using fewer or no medications * Ability to walk independently without an assistive device * Ability to communicate verbally * Voluntary participation in the study * No complaint or diagnosis of vestibular disorder * Ability to read and write Exclusion Criteria: * Individuals younger than 60 years * Severe dementia * Use of an assistive walking device * Central nervous system or visual pathologies that may affect balance * Previous diagnosis of vestibular pathology * History of severe neurological diseases such as stroke * Inability to provide reliable responses to the assessments * Inability to cooperate with the assessment procedures * Inability to read and write

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As listed by the trial registrant

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How to take part

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Contacts and locations

Locations

  • Ondokuz Mayıs University

    Samsun, Samsun, 55139, Turkey (Türkiye)